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題名 | 蛋白尿患者鋅銅營養狀況之探討 |
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作者 | 王果行; 鄭佩玲; | 書刊名 | 中華民國營養學會雜誌 |
卷期 | 18:3/4 民82.10 |
頁次 | 頁151-163 |
分類號 | 411.38 |
關鍵詞 | 血清總蛋白; 白蛋白; 血清鋅; 尿鋅; 血清銅; 藍胞漿素; 尿銅; 飲食鋅及銅; Serum total portein; Albumin; Serum zinc; Urinary zinc; Serum copper; Ceruloplasmin; Urinary copper; Dietary zinc and copper; |
語文 | 中文(Chinese) |
中文摘要 | 本研究之目的在於探討蛋白質與微量元素鋅銅營養狀況之關係。實驗組包括九位肝腎功能正常之住院蛋白尿患者(每日尿蛋白大於2.5克)。病人每日飲食供應為每公斤體重0.8克蛋白質及35仟卡熱量。對照組為26位健康者(SMA-12項目皆在正常範圍)。結果顯示,蛋白尿變化與血清白蛋白改變呈反比現象(r=-0.80,p<0.05),蛋白尿變化與血清總蛋白改變亦呈反比(r=-0.76,p<0.05)。蛋白尿改善後,平均血清鋅值上升(p<0.05),但仍較對照組血鋅值為低(p<0.05)。蛋白尿嚴重期平均尿中鋅排出量亦較蛋白尿改善後為高(p<0.05)。平均血清銅及藍胞漿素皆隨著蛋白尿的減少而改善(p<0.05),但血清銅仍較對照組為低(p<0.05)。血清銅濃度與藍胞漿素值成正相關(r=0.77,p<0.05)。50克及60克限制蛋白質飲食中鋅含量低於RDA建議量,銅則在建議範圍內。 |
英文摘要 | Nine hospitalized pi-oteinuria (>2.5g protein/day) patients with normalhepatic and renal functions were chosen as the experimental group to see therelationship of proteinuria and their mineral nutrition status. Patients were on a diet with 0.8 g protein and 35 kcal per kg of bodyweight. The control group consisted of 26 healthy volunteers whose SMA-12values were all within normal ranges. Results indicated that negative correlationexisted between proteinuria and serum albimin (r=-0.80, p<0.05), proteinuria andserum total protein (r=-0.76, p<0.05). Elevation (p<0.05) of average serum zinclevel occurred after proteinuria improved, however, value was still lower than thecontrol (p<0.05). Meanwhile average total amount of urinary zinc was higherbefore treatment than that of post-treatment. Improvement of serum copper andceruloplasmin were occurred post-treatment (p<0.05), nevertheless, mean serumcopper level of post-treatment patients was lower than that of control group (p<0.05). A positive correlation between serum ceruloplasmin and serum copper (r=0.77, p<0.05) was observed. Copper contents, but not zinc, in the 50g and 60gprotein diets met RDAs. |
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