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題 名 | Relationship between Microalbuminuria, Left Ventricular Mass and Function in Essential Hypertension=高血壓患者微量白蛋白與左心室質量及功能之探討 |
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作 者 | 吳三江; 鄭富榮; 魏淑儀; 蘇清蓉; | 書刊名 | The Kaohsiung Journal of Medical Sciences |
卷 期 | 14:9 1998.09[民87.09] |
頁 次 | 頁536-541 |
分類號 | 415.382 |
關鍵詞 | 高血壓患者; 血壓; 微量白蛋白; 左心室; Microalbuminuria; Hypertension; Left ventricular function; |
語 文 | 英文(English) |
中文摘要 | 為探討高血壓患者血壓,左心室肥大與微量白蛋白之關係,計收集150位高血壓 患者。所有患者接受血壓,尿液中微量白蛋白之測定及胸部X光,心電圖,心臟超音波之檢 查。心臟超音波則包含左心室質量指數,收縮分數,杜普勒流速圖(E/A)。患者依舒張壓高低 劃分為四組。左心室肥大依據心電圖診斷為28位患者(18.7%),胸部X光為56位患者 (37.3%),而心臟超音波則為126位(89.3%)。尿液中微量白蛋白陽性計有42位患者(28%)。 如患者之收縮壓,舒張壓,平均動脈壓愈高,則微量白蛋白陽性率愈高。左心室之功能如收 縮係數,E/A比率與血壓上升並無統計學上之意義。但微量白蛋白與左心室質量指數成正性 相關(p<0.001),亦即微量白蛋白愈高者,左心室質量捐數愈高。生化檢查差異則與微量白蛋 白高低無關。結論指出於原發性高血壓患者,徹量白蛋白與血壓嚴重度有關,高血壓患者如 伴隨微量白蛋白時,左心室質量指數愈高。 |
英文摘要 | To investigate the relationship of microalbuminuria, left ventricular hypertrophy and hypertension, 150 hypertensive patients were studied. All patients received a series of blood pressure (BP) measurements, overnight urine collection for microalbuminuria determination, chest radiography (CXR), electrocardiography (EKG) and echocardiographic assessment. Echocardiographic variables including left ventricular mass index (LVML), fractional shortening (FS) and Doppler mitral flow E/A ratio were analyzed. Patients were divided into 4 groups according to diastolic blood pressure. Left ventricular hypertrophy (LVH) was identified by EKG in 28 patients (18.7%), by CXR in 56 patients (37.3%) and by echocardiography in 126 patients (89.3%). Microalbuminuria was detected in 42 patients (28 %). Microalbuminuria tended to present in patients with higher systolic, diastolic and mean blood pressure. There was no relation between FS and E/A ratio and the degree of blood pressure elevation. However, there was a strong correlation between microalbuminuria and LVMI (p<0.001), this correlation was not related to any difference in blood biochemistry. The results of this study indicate that the severity of microalbuminuria relates closely to the severity of hypertension. In addition, hypertensive patients with microalbuminuria tend to have higher LVMI. |
本系統中英文摘要資訊取自各篇刊載內容。