頁籤選單縮合
題名 | 銅作業勞工血清銅及尿銅濃度調查報告 |
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作者 | 吳正吉; 趙秀雄; | 書刊名 | 醫學研究 |
卷期 | 4:1 1981.01[民70.01] |
頁次 | 頁1147-1155 |
關鍵詞 | 血清銅; 尿銅濃度; 勞工; 銅作業; |
語文 | 中文(Chinese) |
中文摘要 | 經檢查30位非銅作業人員之血清銅含量,平均濃度為95.23±13.6µg/100ml,估計正常無特定銅曝露之成年人血清銅濃度介於80~110µg/100ml之間,此值比歐美報告者為低;男性血清銅含量比女性稍低,與歐美報告者同。非銅作業勞工尿液銅濃度平均為2.08±1.35µg/l,約相當於2~5µg/day,比值遠比歐美報告者為低。可能因人種因素和飲食物中含銅量之差異,造成血清銅和尿銅排泄量之差異。 對國內二家大規模銅作業工廠檢查148位銅作業人員之結果,測得平均血清銅濃度97.70±24.67µg/100ml,尿銅排泄量平均為23.25±16.98µg/l,都比非作業人員為高,且作業年資高者血清銅和尿銅濃度也較高,顯示銅作業人員自其作業環境之曝露中吸收額外之銅,惟吸收過量超過160µg/100ml者只有一人(0.68%),但若以血清銅超過120µg/100ml為篩檢水準,則有16人高於此值,佔10.8%。尿液銅含量以50µg/l為篩檢水準,則有4人(2.7%)超過此限。 目前雖無確定之銅中毒病例發現,但為預防金屬煙熱和日後可能之中毒案例,廠方作業環境安全衛生條件仍有待進一步改善。 銅為人體主要之元素,血清銅不宜低於70µg/100ml,本研究現有14人(7.8%)有銅缺乏現象。銅不足可造成貧血,但本研究發現19位(10.7%)勞工罹患貧血,似乎與銅不足無關。 |
英文摘要 | Copper is one of the important industrial metals, and also an essential trace element of human body. Industrial copper poisoning was rarely found, although some victims of brass-chill had been reported since 1949. The major cause of rarity of this industrial intoxication might be good homestasis for copper metabolism in human body. A survey of industrial copper poisoning was conducted during the period between March to July 1980. 148 copper workers and 30 non-copper workers were examined. The copper concentrations in their serum and spot urine were measured with flame method of atomic absorption spectrophotometry. Past history of any industrial intoxication was taken and evidances of anemia were collected too. The average serum copper levels of copper and non-copper workers were 97.70±24.67µg/100ml and 95.23±13.6µg/100ml respectively. And the average urinary copper levels of them were 23.25±16.98µg/100ml and 2.08±1.35µg/100ml respectively. The serum copper levels of both copper and non-copper workers were higher in female than in male, and higher in the older than the young. The estimated copper level of Chinese, 80-110µg/100ml in serum, and 2.5µg/day in wine, were somewhat lower than that of the European which were 80-160µg/100ml in serum and 0-50µg/day in urine, as reported in literatures. 16 copper workers (10.8%) were found to have their serum copper levels higher than screening level of 120µg/100ml, and 4 copper workers (2.7%) had increased urinary excretion of copper. No case of clinically identified acute or chronic copper poisoning was disclosed in this study, but 7 copper-melting workers complained to have previous episodes of symptoms like brass-chilll. All were self-limited and cured shortly after resting and conservative managements. The possible cause of their attacks might be due to inhalation of zinc-oxide dust, a byproduct of copper melting. 14 workers (7.8%) were revealed to be copper-deficient, but they had no clinical evidances of anemia except 2 of them. Nevertheless, 19 anemic workers (10.7%) were found to be irrelated to their serum copper contents. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。