頁籤選單縮合
題名 | 中醫血虛證型分群在系統性紅斑狼瘡患者的統計分析= |
---|---|
作者 | 蘇奕彰; 李燊銘; 吳文祥; |
期刊 | 中國統計學報 |
出版日期 | 19951200 |
卷期 | 33:4 1995.12[民84.12] |
頁次 | 頁563-580 |
分類號 | 410.028 |
語文 | chi |
關鍵詞 | 問診; 體質; 血虛體質; 最大概似估計量; EM演算法; 潛在變數模型; Inquiring data; Physical constitution; Blood-deficiency type; Maximum likelihood estimator; EM algorithm; Latent variable model; |
中文摘要 | 本主是利用潛在變數模型 (latent variable model) 分折中醫師在台中榮民總醫院所收集250位患有系統性紅斑狼瘡 (systemic lupus erythematosus) 患者的血虛體質問診資料。主要目的是建立中國醫學對血虛體質的診斷基準以提高中醫問診的準確性。中國醫學對於血虛體質的問診部分包含有頭暈、眼花、耳鳴、失眠、心悸及肢麻等六個問項。我們所用的方法是根據此六個問項的問診資料估算潛在變數模型參數的最大概似估計量 (maximum likelihood estimator),再利用估計的結果配合貝氏定理 (Bayes theorem) 中事後機率 (posterior probability) 的觀念進一步建立血虛體質的診斷基準。其結果為:潛在血虛體質與潛在非血虛體質的群體分別佔39%且61%;若以事後機率0.5做為診斷有潛在血虛體質的基準,則當至少三項問診的症狀出現時,可判定為有潛在血虛體質;如果從症狀重要性而言,則可視頭暈、眼花、耳鳴、心悸為主要症狀,失眠及肢麻為次要症狀;當主要症狀出現至少三項,或主要症狀出現兩項且加上次要症狀都出現時,做為有潛在血虛體質的診斷標準,此時所對應的事後機率的可達0.8以上。 |
英文摘要 | In this paper, we apply a latent variable model to analyze the inquiring data of 250 systemic lupus erythematosus (SLE) patients. Data were collected from Taichung Veterans General Hospital, Taiwan. We focus on the patients whose physical constitution is blood-deficiency type. The main purpose of this article is to build a diagnostic criterion, from Chinese medical perspective, for the SLE patients' physical constitution and raise daignostic accuracy. The inquiry for the blood-deficiency physical constitution inc1udes checking six symptoms: vertigo, blurred vision, tinnitus, insomnia, palpitation and numbness of limbs. We find the maximum likelihood estimates for the parameters of the latent variable model and use the concept of the posterior probability in Bayes theorem to build a classification rule. The result is that there are 39% and 61 % of the patients belong to blood-deficiency group and non-blood-deficiency group, respectively. Using the posterior probability greater than 0.5 as a classification rule, we can classify a patient into blood-deficiency group if he/she has three or more symptoms. Furthermore, we treat vertigo, blurred vision, tinnitus, and palpitation as major symptoms, insomnia, and numbness of limbs as minor symptoms. Then we can c1assifya patient into the blood-deficiency group if three or more major symptoms, or two major symptoms plus all the minor symptoms occurred. Under the new diagnostic criterion, the corresponding posterior probability is greater than 0.8. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。