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題 名 | Strength and Functional Performance of Patients with Limb-girdle Muscular Dystrophy=肢帶型肌肉失養症病人之肌力與功能表現 |
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作 者 | 呂怡靜; 陳順勝; | 書刊名 | The Kaohsiung Journal of Medical Sciences |
卷 期 | 16:2 2000.02[民89.02] |
頁 次 | 頁83-90 |
分類號 | 415.9413 |
關鍵詞 | 肢帶型肌肉失養症; 肌力; Limb girdle muscular dystrophy; Manual muscle testing; Motor function; |
語 文 | 英文(English) |
中文摘要 | 肢帶型肌肉失養症( Limb-girdle muscular dystrophy )是屬於遺傳性肌肉疾 病,肌肉無力狀況屬於比較緩慢之進行性肌肉無力。本篇的研究目的為研究分析肢帶型肌肉 失養症病患,自然疾病過程肌力喪失情形、功能狀態以及日常生活能力之表現等。研究方法 以徒手肌力測試評估上下肢肌力,以 Brooke 和 Vignos 評估表來評估上下肢運動功能,以 巴歇爾指數( Barthel index )來評估日常生活能力。 結果發現 48 名肢帶型肌肉失養症 病人肌力下降的情形呈現對稱且漸進式肌力衰退,依據回歸分析發現肌力衰退的速度與患病 時間(年)長短成反比關係, 其方程式為:平均肌力= 0.6052 +( 0.6309/ 患病時間) 。 隨著患病時間越長,肌力下降的速度有漸緩的傾向。上肢運動功能方面 89.6% 病人在等 級 1-3,10.4% 病人在等級 5; 下肢功能方面 79.1% 病人在等級 1-5,一人( 2.1% )在 等級 6 及 18.8% 病人在等級 9。平均巴歇爾指數分數為 85.3 ± 20.7。 肌力與運動功能 以及與日常生活能力表現有顯著相關。本篇研究提供臺灣肢帶型肉失養症病患,自然疾病過 程肌力下降與運動功能以及日常生活能力的表現並探討其相關性,顯示大部分臺灣病患為輕 度或中度肢體障礙,可作為臨床治療肌帶型肌肉失養症病患的參考。 |
英文摘要 | This study was design to reach a better understanding of muscle strength, motor function and activity of daily living in patients of limb-girdle muscular dystrophy. Forty-eight patients diagnosed as cases of limb-girdle muscular dystrophy were included in this study. Manual muscle testing was used to evaluate muscle strength. The Brooke and Vignos scales were used to grade upper and lower extremities function, respectively, and the ability of daily living activity was measured by Barthel index. Our patients showed progressive symmetrical limb-girdle muscular weakness. Upon regression analysis we found that mean muscle strength was inversely related to disease duration (years) as follows: mean muscle strength = 0.6052 + (0.6309 / disease duration). According to the Brooke functional scale, 89.6% of our patients were graded as 1-3 and 10.4% were graded as 5. On the Vignos functional scale, 79.1% of patients fell into the grades 1-5, one person (2.1%) in grade 6 and 18.8% in grade 9 category. The average Barthel index was 85.3 ± 20.7. Mean muscle strength was significantly correlated with the average Barthel, Vignos and Brooke functional scales. Our study could offer the strength and functional performance of limb-girdle muscular dystrophy on natural history. The muscle strength declined in Taiwanese Patients of limbgirdle muscular dystrophy in a typical pattern. Regression analysis showed that the strength was inversely related to disease duration. These findings demonstrate that most of our patients suffered from mild or moderate physical disability. |
本系統中英文摘要資訊取自各篇刊載內容。