查詢結果分析
相關文獻
- Seafood Allergy: Tropomyosins and Beyond
- 養陰克敏方對兒童氣喘療效之研究
- Characterization of Allergens of Penicillium and Aspergillus Species
- Effects of Ozone on Ovalbumin Sensitization in Guinea Pigs
- Inflammatory, Immunological and Clinical Comparisons of Short- and Long-acting Bronchodilators in Mild and Moderate Bronchial Asthma Patients
- Comparison of Indoor Allergens, Allergic Scores, and Demographic Data in Taiwanese Adults with Asthma or Allergic Rhinitis, or Both
- 各年齡層氣喘病人室內吸入性過敏原過敏率與過敏程度之研究
- 由過敏原談日本人杉木花粉症的預防對策
- 過敏原及其毒性檢驗法之探討
- 過敏原及其毒性檢驗法之探討
頁籤選單縮合
題名 | Seafood Allergy: Tropomyosins and Beyond=海鮮過敏:旋肌蛋白及其展望 |
---|---|
作者姓名(中文) | 梁世昌; 陳彥蓁; 朱家濠; | 書刊名 | 微免與感染雜誌 |
卷期 | 32:3 1999.09[民88.09] |
頁次 | 頁143-154 |
分類號 | 415.96 |
關鍵詞 | 過敏; 旋肌蛋白; 過敏原; Hypersensitivity; IgE; Allergen; cDNA; Tropomyosin; Epitopes; |
語文 | 英文(English) |
中文摘要 | 海鮮引起的過敏反應是最常見的食物過敏之一。雖然經過多年的研究努力,為何有特定的人口會對海鮮過敏至今仍然不是很清楚。由於對海鮮的需求量日漸增加,也造成海鮮過敏的危險性跟著提高,所以進一步研究海鮮過敏的分子機制和以分子生物的方法來找出海鮮過敏原已經是刻不容緩。在本篇文章中我們將進一步討論有殼海鮮過敏的臨床症狀、生理機轉、目前有關有殼海鮮免疫學及分子機制,以及未來避免有殼海鮮過敏發生的方向。令人感到興趣的是目前找到的海鮮過敏原是一群肌肉蛋白,如鱈魚的卵巢蛋白及甲殼類的旋肌蛋白(tropomyosin)。同時,有非常明顯的免疫學證據顯示旋肌蛋白在甲殼類和軟體動物類有交叉反應的情形。海鮮過敏原的分子選殖、表現及生化的特徵研究都將提供我們進一步了解海鮮過敏原機轉及研發免疫調節方法的重要工具。 |
英文摘要 | Hypersensitive reactions to seafood is one of the most common food allergies. Despite years of intensive studies, the reasons why some people are allergic to seafood is still unclear. The growing demand for seafood and the subsequent increasing risk of seafood allergy in the population at large make it important to elucidate the molecular basis of seafood allergy and identify the seafood allergens at the molecular level. Here, we discuss the clinical symptoms, physiological mechanisms, current findings of the immunological and molecular basis of shellfish allergy as well as future directions for the prevention of shellfish allergy. Interestingly, identified seafood allergens belong to a group of muscle proteins, namely the parvalbumins in codfish and tropomyosin in crustaceans. In addition, there is strong immunological evidence that tropomyosin is a cross-reactive allergen among crustaceans and mollusks. The molecular cloning, expression and biochemical characterization of seafood allergens will continue to provide valuable tools in the further understanding of the mechanisms of seafood allergy as well as the future development of immunomodulation regimen. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。