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題名 | Comparison of Indoor Allergens, Allergic Scores, and Demographic Data in Taiwanese Adults with Asthma or Allergic Rhinitis, or Both=比較臺灣哮喘或過敏性鼻炎成人在室內過敏原,過敏指數及人口學資料上之差別 |
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作者 | 李立夫; 林孟志; 楊政達; 謝孟哲; 黃崇旂; 史麗珠; 曹昌堯; | 書刊名 | 臺灣醫學會雜誌 |
卷期 | 98:7 1999.07[民88.07] |
頁次 | 頁486-491 |
分類號 | 415.96 |
關鍵詞 | 哮喘; 過敏性鼻炎; 室內過敏原; Asthma; Allergic rhinitis; Atopy; Indoor allergen; Enzyme-linked immunosorbent assay; |
語文 | 英文(English) |
英文摘要 | We examined the relationships between exposure to different indoor allergens and demographic factors in 515 adult Taiwanese patients with allergic diseases such as asthma and rhinitis. Patients who had positive screening results on an immunoglobulin E (IgE) test were recruited from the outpatient clinics of Chang Gung Memorial Hospital. Patients were divided into the following three groups: asthma (n = 332), combined asthma and allergic rhinitis (n = 165), and allergic rhinitis (n = 18). Serum samples were analyzed for IgE by enzyme-linked immunosorbent assay. Significantly elevated titer of dust mite-specific IgE were found in all three groups, with markedly higher levels in the combined asthma and allergic rhinitis group (p< 0.05). Allergen scores were significantly related to the demographic variables of older age (≧ 65 years), female gender, and spring season, with significantly lower scores (p < 0.05). No significant difference in allergen scores was found among cigarette smoking subjects and subjects from residential areas. Multiple linear regression analysis revealed significant allergic contributors to be, in order of importance, age, gender, and atopic disease category. We conclude that mite allergen exposure is the most significant factor associated with asthma and/or allergic rhinitis in Taiwan. Younger subjects and males had a higher rate of asthma and/or allergic rhinitis. |
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