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題名 | 各年齡層氣喘病人室內吸入性過敏原過敏率與過敏程度之研究=Different Age of Asthmatic Patients Affected by Different Aeroallergens |
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作者 | 蔡肇基; 陳五常; | 書刊名 | 微免與感染雜誌 |
卷期 | 32:4 1999.12[民88.12] |
頁次 | 頁283-288 |
分類號 | 415.425 |
關鍵詞 | 氣喘; 吸入性過敏原; Asthma; Aeroallergens; |
語文 | 中文(Chinese) |
中文摘要 | 我們統計1070位各年齡層氣喘病人室內三種最常見的吸入性過敏原,家塵�臐B蟑螂、黴菌之過敏率與過敏程度,並且依病人血清中過敏原特異型抗體IgE之濃度高低分過敏程度為嚴重、中度及輕度三種,結果發現有77.9%病人對家塵�薾L敏,40.0%對德國蟑螂過敏,10.4%對Penicillium notatum 過敏,9.6%對Candida albicans過敏。若依年齡來分析家塵�薾L敏率以年齡在11歲到20歲之間為最高96.8%,且過敏程度達嚴重過敏之比率最高為70%。黴菌過敏的發生率P. notatum在60歲以上最高為18.9%,C. albicans在51歲至60歲最高為27.3%,稻大都為輕度過敏,蟑螂過敏的發生率在21歲至30歲之間為最高55.4%且過敏程度達中等程度過敏的比率也最高為23.2%。因此我們認為氣喘病人室內吸入性過敏原以家塵�薾L敏最早發生,在11歲至20歲就達最高點,而且過敏程嚴重之機率最高;其次是蟑螂過敏在21歲到30歲之間達最高點,而且過敏程度達中度過敏之機率僅有四分之一;黴菌過敏則最晚發生,在51歲以後才達最高點,而過敏程度都屬輕微。因此:吸入性過敏原當中,不論過敏機率以及過敏程度都以家塵�薾L敏最為嚴重且最早發生。 |
英文摘要 | A total of 1070 cases of bronchial asthma, aged from 3 to 70 years, were analyzed for their hypersensitivity to the four most common aeroallergens, Dermatophagoides pteronyssinus, German cockroaches, Penicilliuim notatum and Candida albicans. The severity of hypersensitivity was classified as mild, moderate and severe based on the concentration of allergen specific IgE in the sera. Results showed that there were 77.9% patients allergic to D. pteronyssinus, 40.0% to G. cockroaches, 9.6% to P. notatum and 10.4% to C. albicans. The incidence and severity varied with age. For D. pteronyssinus, the highest incidence was 96.8% with the age between 11 and 20 years. Seventy percent of them were severe hypersensitivity. For P. notatum, the highest incidence was 18.9% with the age above 61 years. None of them were severe hypersensitivity and 11.9% of them were moderate hypersensitivity. For C. albicans, the highest incidence was 27.3% with the age be-tween 51 and 60 years. All of them were mild hypersensitivity. For G. cockroaches, the highest incidence was 55.4% with the age between 21 and 30 years. 76.8% of them were mild hypersensitivity and 23.2% were moderate hypersensitivity. We concluded that different age of asthmatic patients affected by different aeroallergens. D. pteronyssinus was the most potent aeroallergen. Most asthmatic patients sensitized by mite were severe, particularly those patients with the age below 20 years of ageo |
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