查詢結果分析
相關文獻
- Thymectomy for Patients with Myasthenia Gravis:Factors Influencing the Outcome
- 重症肌無力的外科治療--胸腺切除術
- Complicated Urinary Tract Infection: Analysis of 179 Patients
- Prognostic Factors in Node-Negative Breast Cancer Patients: The Experience in Taiwan
- Reentry of a Treated Advanced Periodontal Lesion with an Acute Abscess--A Case Report
- Postoperative Radiotherapy of Adult Supratentorial High-grade Astrocytoma
- Prenatal Diagnosis and Perinatal Outcome of Facial Clefts
- Shock in the Pediatric Emergency Service: Five Years' Experience
- 糖尿病與腦中風
- The Prognostic Significance of Pathologic Characteristics of Breast Cancer Patients in Taiwan
頁籤選單縮合
題 名 | Thymectomy for Patients with Myasthenia Gravis:Factors Influencing the Outcome=重症肌無力病人接受胸腺切除後預後影響因子分析評估 |
---|---|
作 者 | 陸希平; 張逸良; 陳晉興; 黃重傑; 李元麒; | 書刊名 | 中華民國外科醫學會雜誌 |
卷 期 | 30:5 民86.09-10 |
頁 次 | 頁329-337 |
分類號 | 415.9413 |
關鍵詞 | 重症肌無力病人; 胸腺切除; 預後; Myasthenia gravis; Thymectomy; |
語 文 | 英文(English) |
英文摘要 | 臺大醫院自 1983 年七月至 1994 年五月期間共有 70 位病人因重症肌無力而接 受胸腺切除手術並接受完整追蹤。 病人當中有 25 位男性與 45 位女性,平均年齡為 36.5 歲。 其中有 23 位( 33.9% )的病人合併有胸腺瘤。重症肌無力診斷方法包括臨床症狀, tensilon 試驗,肌電圖測驗以及乙醯膽鹼受體單株抗體效價等等。 電腦斷層檢查用以發覺 合併胸腺瘤的存在。病人於術前中後評估分期並定期追蹤。在本系列病人當中無術中死亡例 , 有兩位病人於術後因重症肌無力而須使用較長期的呼吸器(超過 7 天),兩位病人於追 蹤過程中死於胸腺瘤復發及轉移。胸腺切除後重症肌無力症狀改善的程度與各種因子,諸如 年齡、性別、胸腺瘤存否,術前重症肌無力存在期間,重症肌無力分期以及胸腺瘤分期等因 素作多變項分析。 在本系列病人當中,手術後獲得完全緩解及改善的比例分別為 35.7% 以 及 87.1%。而胸腺瘤的存在與否是影響預後的最明顯因子。在本研究亦發現合併胸腺瘤的重 症肌無力相對好發於年紀大之病人,而單純重症肌無力者則好發於年輕之女性病人。而胸腺 切除對此類病人而言,是十分有效及安全的治療方式。 hymothymectomy through sternotomy or sternothoracotomy was undertaken for ones with thymomatous MG. No postoperative death was noted and only two patients, showing MG symptoms, needed prolonged ventilatory support (>7 days) postoperatively. However, two patients died of thymoma recurrence or metastasis. The outcome (remission and surgical beneficial curve) was analyzed, and the possible influencing factor such as age, sex, existence of thymoma, MG duration before thymectomy, MG staging or the pathology of thymus, was analyzed based on the univariate and multivariate Cox model. The surgical remission and beneficial rates for the presant patients, at the end of follow-up period, are 35.7% and 87.1% respectively, and the existence of thymoma is found to be the single most significant factor of which adversely influences the outcome. In this series it was also found that younger (<40 years old) or female patients have significantly higher possibility of acquiring simple MG, than the male or older patients. It may hence be concluded that thymectomy is an effective treatment for patients with MG, and also that patients with thymomatous MG are likely to suffer a worse outcome than the ones with simple MG. |
本系統中英文摘要資訊取自各篇刊載內容。