查詢結果分析
相關文獻
- Postoperative Radiotherapy of Adult Supratentorial High-grade Astrocytoma
- 成人低惡性度顱內星狀細胞瘤之術後放射治療
- Prognostic Factors and Results of Radiotherapy for Brain Stem Gliomas
- Remotely Controllable Temporary Afterloading Brachytherapy for Malignant Brain Tumors
- 第四期鼻咽癌的預後因子
- Palliative Radiotherapy for Synchronous Brain Metastases from Lung Cancer
- Analysis of Prognostic Factors of Oral Cavity Squamous Cell Carcinoma Patients Receiving Surgery
- Postoperative Rodiotherapy in Rectal Cancer: Analysis of Local Control, Surviral and Prognostic Factors
- Clinical Implications of Tumor Volume in Patients with the Base of Tongue Cancer Treated with Definitive Intensity-modulated Radiotherapy Technique
- Treatment Results and Prognostic Factors for Locally Advanced Buccal Cancer
頁籤選單縮合
題 名 | Postoperative Radiotherapy of Adult Supratentorial High-grade Astrocytoma=成人惡性星狀細胞腦瘤之術後放射治療 |
---|---|
作 者 | 陳尚文; 容世明; 林芳仁; 曾振淦; 陳文政; 張東杰; 洪志宏; | 書刊名 | 中華放射線醫學雜誌 |
卷 期 | 24:1 1999.02[民88.02] |
頁 次 | 頁15-20 |
分類號 | 416.36 |
關鍵詞 | 惡性腦瘤; 放射治療; 預後因子; Brain neoplasm; High-grade astrocytoma; Radiotherapy; Prognostic factors; |
語 文 | 英文(English) |
中文摘要 | 了解高惡性度星狀細胞腦瘤病人接受術後放射治療之預後因子。自1979年至1988年,有79位病人,經組織切片證實之高惡性星狀細胞腦瘤,在林口長庚醫院完成術後放射治療。27位病人接受完全腫瘤切除,32位接受部份切除,20位只接受定位切片。31位患者之病理報告為Kernohan第三級,48位患者為第四級。56位為男性,23位為女性。患者年紀、性別,Kernohan病理分期,手術範圍;治療之方式,及輻射劑量,進入單變數及多變數分析。二年的存活率為15中間值存活為46週。年紀病理分期及手術範圍會影響到預後。病人接受一日多次放射治療並沒有此傳統放射治療好。針對49位接受傳統放射治療之患者做單變數及多變數分析發現Kernohan病理分期,手術範圍及腫瘤輻射劑量都是獨立的預後因子。對於高惡性度的腦瘤,完全的腫瘤切除及提高腫瘤輻射劑量都可提高患者的存活。 |
英文摘要 | To find the prognostic factors ofhigh grade glioma patients treated by postoperative radiotherapy.From 1979 through 1988, 79patients with proven supratentorialhigh-grade astrocytoma completedexternal beam irradiation at ChangChung Memorial Hospital followingsurgery, including by total removal(27 patients); subtotal removal (32patients) or biopsy only (20patients). Thirty-one patients and48 (60.8) patients had Kernohangrade III tumors and Glioblastomamultiform, respectively. There were56 male (70.9) and 23 femalepatients. Median age at time ofdiagnosis was 40 years (range, 15to 69 years). The patients weresubject to univariate andmultivariate analyses according toage, sex, Kernohan grading, extentof surgery, treatment modality, andirradiation dose. Overall 2-yearsurvival was 15 and mediansurvival was 46 weeks. Improvedsurvival were much more likely inpatients younger than 40 years p=0.016), with Kernohan grade IIItumors (p=0.002), and those whounderwent surgical excision(p=0.001). Multiple dailyfractionation (30 patients) did notlengthen patient survival whencompared with conventionalradiotherapy (49 patients). For the49 patients treated withconventional radiotherapy, the doseappeared to be associated withlengthened survival (p=0.037).Multivariate analysis using Cox'sproportional hazard model for the49 patients treated usingconventional therapy showedKernohan grade, extent of surgery,and irradiation dose wereindependent prognostic factors.Tumor pathological grade, extent ofsurgery and radiation dose wereimportant prognostic factors inpatients with high-gradeastrocytoma. More extensivesurgery and higher postoperativeradiation dose lengthened thesurvival in patients with high-gradeastrocytoma. |
本系統中英文摘要資訊取自各篇刊載內容。