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題 名 | The Prognostic Significance of Pathologic Characteristics of Breast Cancer Patients in Taiwan=乳癌的病理特徵在預後的重要性 |
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作 者 | 朱娟秀; 黃俊升; 張金堅; | 書刊名 | 慈濟醫學 |
卷 期 | 10:4 1998.12[民87.12] |
頁 次 | 頁265-271 |
分類號 | 416.226 |
關鍵詞 | 乳癌; 病理; 預後; Breast cancer; Pathology; Prognosis; |
語 文 | 英文(English) |
英文摘要 | To investigate the prognostic significance of pathologic characteristics of breast cancer patients, we retrospectively studied 514 patients with operable cancer from 1978 through 1987. The mean age of the patients was 50.2 ± 12.4 years. Tumor sizes ranged from 0.7 to 13.0 cm, with a mean size of 4.26 ± 2.4 cm. Axillary node metastases were found in 56.4% of the patients. Univariate analysis on the survival rate revealed that the number of positive nodes, tumor size, lymphatic permeation, tumor necrosis, histologic type, histologic grade, and age were significant prognostic factors. Multivariate Cox regression analysis showed that the number of positive nodes (p<0.00005) , histologic grade (p=0.0002), and tumor size (p=0.0108) were independent prognostic factors. Our study confirms the importance of pathologic characteristics in predicting the prognosis of breast cancer patients. (Tzu Chi Med J 1998;10:265-271) |
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