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| 題 名 | THE Study OF Prognostic Factors in Guillain- Barre Syndrome=Guillain-Barre 症候群的預後因素研究 |
|---|---|
| 作 者 | 丁廣祥; | 書刊名 | 醫學研究 |
| 卷 期 | 12:6 1992.05[民81.05] |
| 頁 次 | 頁410-419 |
| 分類號 | 415.828 |
| 關鍵詞 | Guillain-Barre症候群; 預後; |
| 語 文 | 英文(English) |
| 中文摘要 | Guillain-Barré症候群為最常見之急性髓鞘脫失多發性神經病變,是目前造成急性下肢行動障礙的主因之一。本科自1985至1990年,共計31例病患,經持續追蹤並由其臨床發現及電生理檢查結果加以探討其預後因素,可得到以下結論: 一、合併先發感染及急性肝炎患者,或接受肝炎疫苗者比率較高,但此因素與預後無關。 二、併發自主神經功能異常或呼吸衰竭病患,預後不佳。 三、腦脊髓液蛋白質量超過200mg/dl,患者預後較差。 四、神經電生理檢查若出現混合肌肉反應電位(compound muscle action potential)之振幅明顯降低(低於正常50%以下者)及肌電圖異常者,其預後較差。而神經傳導速度與預後並無明顯關聯。 |
| 英文摘要 | Guillain-Barré syndrome (GBS) is the most common cause of acute inflammatory demyelinating disease. We studied the clinical course and electrophysiologic findings of GBS in 31 patients from 1985 to 1990. The result of the study suggested the incidence of antecedent illness and viral Hepatitis-B associated patients or Hepatitis-B vaccination induced GBS were higher than those from other reports. These antecedent or associated illnesses had no influence on the outcome of GBS. The major clinical indicator of a poor prognosis was autonomic dysfunction and ventilatory failure. High levels of protein (>200 mg/dl) in the cerebrospinal fluid (CSF) were also observed in the patients with poor prognosis. These patients markedly reduced the amplitude of compound muscle action potential (CMAP) and had electromyogram (EMG) abnormalities. Nerve conduction velocity (NCV) had no direct influence on the outcome of GBS. |
本系統中英文摘要資訊取自各篇刊載內容。