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題名 | The Effect of Prostate Massage on Serum Prostatic Acid Phosphatase Level: A Study with Enzymatic and Radioimmunologic Assay=生化酵素及放射性免疫分析法評估攝護腺按摩對血清酸性燐酸鹽酵素之影響 |
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作者 | 李瀛輝; | 書刊名 | 中華民國外科醫學會雜誌 |
卷期 | 20:6 1987.11[民76.11] |
頁次 | 頁508-513 |
分類號 | 416.275 |
關鍵詞 | 生化酵素; 放射性免疫分析法; 攝護腺按摩; 血清; 酸性燐酸鹽酵素; |
語文 | 英文(English) |
中文摘要 | 攝護腺按摩對血清酸性燐燒酵素之影響值增加,而導致診斷攝護腺癌之困擾,目前眾說紛云,尚無定論。 我們利用生化酵素分析法和放射性免疫分析法測定血清酸性燐燒酵素,做了一項前瞻性研究。總共44位病人分成兩組,第一組33位病人,屬良性攝護腺肥大症患者,第二組11位病人,屬尿路結石患者;每一組病人分別在攝護腺按摩前,攝護腺按摩後1, 6, 12, 24, 48小時,以生化酵索及放射性免疫分析法測定血清酸性燐燒酵素之變化情形。研究結果顯示:(一)兩組病人酸性燐燒酵素值無明顯差異。(二)良性攝護腺肥大症組之病人,在以免疫分析法測定攝護體按摩後1小時之酸性燐燒酵素值及尿路結石患者組在以生化酵素法測定攝護腺按摩後12小時和以免疫分析法測定攝護腺按摩後1, 12小時之酸性燐燒酵素值,均較按摩前之酸性燐燒酵素值為高,同時有統計學上之意義,但是其增高之程度仍在正常血清酸性燐酸鹽範圍內,不致於造成診斷攝護腺癌之困擾,因此我們認為血清內酸性燐酸鹽酵素之測定,可在任何時間檢查,並不需要在攝護腺按摩或檢查後24小時才檢查。 |
英文摘要 | A prospective study was done to evaluate the effect of prostate massage on serum prostatic acid phosphatase as reviewed by enzymatic and radioimmunologic assay: Of 44 patients studied, 33 were diagnosed as benign prostatic hyperplasia; 11 patients were the control group. Blood samples were withdrawn before prostate massage and at 1, 6, 12, 24, and 48 hours after prostate massage. The acid phosphatase increased at 12hr after prostate massage in the control group as detennined by enzymatic assay; acid phosphatase increased at 1hr after prostate massage in the BPH group, 1hr, then 12hr after prostate massage in the control group by radioimmunologic assay, with statistical significance, but none of these data reached an abnonnal level to cause suspicion of the possibility of prostatic malignancy. It appears that the timing of blood sampling is not so crucial for detection of serumacid phosphatase. |
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