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題名 | 預測中老年期停經婦女低骨質密度的危險因素=Predicting Factors for Bone Mineral Density Among Postmenopausal Women |
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作者 | 李燕鳴; 曾慶孝; 劉淑馨; | 書刊名 | 臺灣老年醫學暨老年學雜誌 |
卷期 | 4:1 2009.02[民98.02] |
頁次 | 頁39-50 |
分類號 | 412.58 |
關鍵詞 | 停經婦女; 骨質密度; 骨質疏鬆症; Bone mineral density; Postmenopausal women; Osteoporosis; |
語文 | 中文(Chinese) |
中文摘要 | 目的:骨質疏鬆症是複雜和花費很高的疾病,亦嚴重威脅老人健康及生活品質,本文評估影響 65歲前後停經婦女低骨質密度的相關危險因素。 方法:研究對象為東臺灣一所教學醫院接受健康檢查的民眾,並由受檢者自填一份健康問卷,內容包括人口學特性、飲食、生活習慣、生育和健康疾病史等。骨質密度以雙能量 X光吸收儀在脊椎(平均第 1至 4節)前後徑測定,並依世界衛生組織的診斷標準定義骨質疏鬆症。以 65歲為分界將受試者分為「中年組」(<65歲)和「老年組」(≥65歲),並以多變項迴歸分析等統計方法評估兩組婦女的骨質密度測定結果和其預測影響因素。 結果:從 412位年齡 50-74歲停經後婦女的資料分析,發現全體受檢婦女之骨質密度平均值是 0.83 (±0.15) g/cm2,其中老年組婦女的骨質密度為 0.77 g/cm2,明顯低於中年組之 0.85 g/cm2 ( p < 0.001)。經診斷為「骨質疏鬆症」的比例,中年組是 32.7%,在老年組是 52.0%。預測停經後婦女骨質密度的重要因素包括「目前體重」和「年齡」;「生育數」在中年組婦女為重要,在「老年組」發現「補充鈣片」和「曾補充荷爾蒙」亦是重要預測因素。 結論:不少停經後婦女的骨質密度已達易骨折的危險程度,「高齡」和「低體重」是預測低骨質密度的重要危險因素。 |
英文摘要 | Objectives: Osteoporosis is a complicated disease/disorder/condition incurring high medical care expense and threatening both elderly health and their life quality. In this paper we examined the results of bone mineral density (BMD) testing among postmenopausal women in an effort to identify factors for predicting BMD. Methods: Women who had health check-ups at a teaching hospital in eastern Taiwan were invited to participate in this study. A self-administered questionnaire was used to collect their demographic characteristics, diet, lifestyles, and reproductive and medical history. Bone mineral density (BMD) of the posterior-anterior lumbar spine (L1- L4) was measured by dual energy x-ray absorptiometry. A diagnosis of osteoporosis was made according to World Health Organization criteria. Women were categorized into “middle age” (age < 65 years) and “elderly” (age≥65 years). Multiple logistic regression analysis was used to assess the significant factors predicting BMD in each group. Results: Data from 412 postmenopausal women, aged 50 to 74 years, were included in this study. The mean BMD read 0.83 (±0.15) g/cm2 while the average BMD of the “elderly” group was significantly lower than that of the “middle age” (0.77 g/cm2 vs 0.85 g/cm2 ). The proportion of osteoporosis (T-score ≦-2.5) was about 32.7% for “middle age” and 52.0% for the “elderly”. Current body weight and age were significant factors predicting BMD in both groups. Parity was also significant for middle age. For elderly, calcium supplement and estrogen supplement were additional factors predicating BMD. Conclusion: A substantive proportion of postmenopausal women have BMD at risk of fragile fracture. Old age and low body weight are significant factors indicating low BMD. |
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