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題 名 | Determination of Lead, Cadmium, Chromium, and Arsenic in 13 Herbs of Tocolysis Formulation Using Atomic Absorption Spectrometry=原子吸收光譜定量分析安胎劑中鉛、鎘、鉻及砷的含量 |
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作 者 | 傅傳博; 林蕙雅; 蔡惠燕; | 書刊名 | 藥物食品分析 |
卷 期 | 11:1 2003.03[民92.03] |
頁 次 | 頁39-45+74 |
分類號 | 341.95 |
關鍵詞 | 安胎劑; 樣品前處理; 原子吸收光譜; Tocolysis formulation; Sample pretreatments; Atomic absorption spectrometry; |
語 文 | 英文(English) |
中文摘要 | 本篇使用3種不同的前處理方法與原子吸收光譜來定量安胎劑中所含13種中藥中鉛,鎘,鉻,砷四種元素的含量。乾式灰化,濕式消化,和微波消化3種前處理方法被用來比較安胎劑13種中藥中所含鉛,鎘,鉻,砷之回收率與精密度。乾式灰化,濕式消化,和微波消化的平均回收率分別為80 ± 12%,85.7 ± 3.3%, and 94.5 ± 2.1 %而其測量四種元素的平均相對標準偏差分別為8.8 ± 1.79%, 7.1 ± 3.39%, and 3.4土0.8%。微波消化前處理與原子吸收光譜對鉛,鎘,鉻,砷的偵測極限分別為0.45ppb, 0.03 ppb , 0.20ppb , and 0.64 ppb而其測量的種中葉中所含鉛,鎘,鉻,砷之平均濃度分別為28.0 ± 0.7 ppb , 1.11 ± 0.03ppb,8.5 ± 0.3 ppb , and 1.52 ± 0.04ppb ,在13種中藥中荊芥含最高之鉛 (60.5 ± 2.1 ppb) ,鉻 (23.3 ± 0.5 ppb) ,及砷 (8.8 ± 0.1 ppb) 而川芎含最高之鎘 (3.76 ± 0.04 ppb)。 |
英文摘要 | The contents of Pb, Cd, Cr, and As in 13 herbs of tocolysis formulations were studied using three kinds of sample pretreatment and atomic absorption spectrometry. Thirteen herbs were pretreated with either incineration, wet digestion, or microwave digestion, and the results of recoveries and precision about these elements were compared. The average recoveries of 13 herbs via incineration, wet digestion, and microwave digestion pretreatments were 80 ± 12%, 85.7 ± 3.3%, and 94.5 ± 2.1%, respectively. Among them, microwave digestion pretreatment had the highest recovery and precision. The average relative standard deviations for the four measured elements (Pb, Cd, Cr, and As) from incineration, wet digestion, and microwave digestion pretreatments were 8.8 ± 1.7%, 7.1 ± 3.3%, and 3.4 ± 0.8%, respectively. The detection limits for Pb, Cd, Cr, and As using microwave digestion pretreatment were 0.45 ppb, 0.03 ppb, 0.20 ppb, and 0.64 ppb, respectively. Concentrations of Pb, Cd, Cr, and As measured from the tocolysis formulation using microwave digestion pretreatment were 28.0 ± 0.7 ppb, 1.11 ± 0.03 ppb, 8.5 ± 0.3 ppb, and 1.52 ± 0.04 ppb, respectively. Lead was found to have the highest concentration among the four determined elements in 13 herbs. Schizonepetae Herba contained the highest Pb (60.5 ± 2.1 ppb), Cr (23.3 ± 0.5 ppb), and As (8.8 ± 0.1 ppb) among the 13 herbs. Ligustici Rhizoma contained the highest Cd (3.76 ± 0.04 ppb) among the 13 herbs. |
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