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頁籤選單縮合
題名 | Lower Serum Albumin Levels in Patients with Mood Disorders=情感性疾病患者之血清白蛋白濃度 |
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作者 | 黃條來; Huang, Tiao-lai; |
期刊 | 長庚醫學 |
出版日期 | 20020800 |
卷期 | 25:8 2002.08[民91.08] |
頁次 | 頁509-513 |
分類號 | 415.985 |
語文 | eng |
關鍵詞 | 白蛋白; 躁症; 重憂鬱症; 自殺; Albumin; Mania; Major depression; Bipolar disorder; Suicide attempt; |
中文摘要 | 背景:在西方國家已有許多報告指出曾有較低的血清白蛋白和情感性疾病有關。本研究將調查是否在臺灣的精神科住院病人其血清白蛋白在疾病急性發作期亦有較低的現象。 方法:回顧南部某醫學中心其精神科在某一年213位急性住院病人中念有61位情感性疾病。記錄其年紀、體重、身高、有無自殺行為、血中白蛋白濃度、血中常見的生化檢查等資料。對照組資料來自病房32位健康的工作同仁。並利用共變異分析等統計方法分析比較情感疾病患者的血中白蛋白濃度與32位精神科工作同仁的資料是否有差異。 結果:25位躁症患者血中平均白蛋白濃度為40.2±4.0克/升。36位重憂鬱症患者血中平均白蛋白濃度為39.8±2.8克/升。而正常組其血中平均白蛋白濃度為45.8±2.0克/升。統計的結果,躁症患者及重憂鬱症患者其血中平均白蛋白濃度皆較正常組為低,有顯著的差異。但在重憂鬱症患者中,有無自殺行為其血中平均白蛋白濃度並無統計上顯著的差異。 結論:在臺灣的情感性疾病住院院人其血清白蛋白濃度在急性發作期亦有較低的現象。 |
英文摘要 | Backgorund: some physicians heave reported lower serum albumin levels in patients with major depression in Western countries. In the study, the relationship between serum albumin levels and mood disorders (including mania and major depression) was investigated during the acute phases in Taiwanese psychiatric inpatients. Methods: A review of medical charts during a 1-year period was carried out in a population of 213 Taiwanese psychiatric inpatients that included 61 patients with mood disorders (with or without suicide attempts). The collected data included age, body weight, height, serum albumin levels, and routine blood biochemistry examination results. These data were compared with data from a healthy control group (N=32) drawn from the staff of the psychiatric ward. Statistical analysis was done using covariance after age adjustment. Results: The mean serum albumin levels were 40.2±4.0 g/L in patients with mania (N=25), 39.8±2.8 g/L in patients with major depression (N=36), and 45.8±2.0 g/L in the control group. Patients with mania (F=64.4, p=0.000) and major depression (F=68.9 , p=0.000), respectively, had significantly lower albumin levels than the control group after age adjustment. However, for the patients with major depression, no significant difference in serum albumin levels were found between patients who had attempted suicide and those who had not. Conclusion: Lower serum albumin levels were noted during the acute phases of mania and major depression in Taiwanese psychiatric inpatients. |
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