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題名 | Serum Cholesterol Levels and Prevalence of Hypercholesterolemia in School-Aged Taiwanese Children and Adolescents: The Taichung Study=學齡兒童及青少年血清中膽固醇值及高膽固醇血症之盛行率:臺中市之研究 |
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作者 | 林正介; 賴明美; 劉秋松; 李采娟; | 書刊名 | 中華醫學雜誌 |
卷期 | 62:11 1999.11[民88.11] |
頁次 | 頁787-794 |
分類號 | 415.38 |
關鍵詞 | 青少年; 小孩; 膽固醇; 高膽固醇血症; 盛行率; Adolescent; Children; Cholesterol; Hypercholesterolemia; Prevalence; |
語文 | 英文(English) |
中文摘要 | 背景:近年,冠狀動脈心臟病已位居臺灣地區的十大死因之一。由於高膽固醇血症是冠狀動脈心臟病的重要危險因子,因此本研究的目的是了解臺灣地區學童及青少年之血中總膽固醇值及高膽固醇血症之盛行率。 方法:本研究以臺中市國小一、四年級及國中一年級的學童為研究對象。共有國小52所及國中26所。經兩階段取樣後共選取了4,520位學生,而實際參與者為3,924位,反應率為86.8%,其中男生2,070位,女性1,854位。學童的年齡為7-14歲。除了測量他們血中總膽固醇值及進行脂蛋白分析外,並計算學童高膽固醇血症之盛行率。 結果:本研究屬於斷代式研究。測得男女學童各血脂肪參數之平均值與標準差分別為:總膽固醇;162 ± 28及165 ± 29 mg/dl;三酸甘油酯:74 ± 33及80 ± 32 mg/dl;高密度脂蛋白-膽固醇:61 ± 13及59 ± 12 mg/dl;低密度脂蛋白-膽固醇:87 ± 24及90 ± 25mg/dl。依不同年齡層分佈之平均總膽固醇值,男生為149-172 mg/dl,女生為157-170 mg/dl。男生總膽固醇值在11歲最高(172 mg/dl),女生則於7歲最高(170 mg/dl)。整體而言,邊緣性高膽固醇血症及高膽固醇血症(總膽固醇值≧170 mg/dl)之盛行率,男生為36.5%(13.5-53.1%),女生為39.7%(28.3-48.6%)。此外,高膽固醇血症(總膽固醇值≧200 mg/dl)之盛行率,男生為9.7%(3.1-16.6%);女生為10.3%(5.0-14.9%)。 結論:不分年齡層或性別,邊緣性高膽固醇血症及高膽固醇血症以總膽固醇值或低密度脂蛋白-膽固醇值為標準之盛行率分別是38.0及17.2%;而高膽固醇血症之盛行率則分別是9.9%及5.8%。與美國學童比較,臺灣學童有較高的三酸甘油酯及高密度脂蛋白-膽固醇值。 |
英文摘要 | Background: Atherosclerosis has become one of the leading causes of death in Taiwan. Hypercholesterolemia is a major risk factor for coronary atherosclerosis. To evaluate the mean total cholesterol values and the prevalence of hypercholesterolemia in school-aged Taiwanese children and adolescents, an epidemiologic survey was conducted. Methods: After two-stage sampling of 52 primary schools and 26 junior high schools in Taichung City, we randomly selected 3,924 children (2,070 boys and 1,854 girls). Blood total cholesterol (TC), triglyceride (TG) and high-density lipoprotein (HDL)-cholesterol were measured. Response rate was 86.8%. Subjects' ages ranged from seven to 14 years old. Results: From this cross-sectional survey, the following characteristics (mean ± SD) were documented for boys and girls, respectively: TC, 162 ± 28 and 165 ± 29 mg/dl; TG, 74 ± 33 and 80 ± 32 mg/dl; HDL-cholesterol, 61 ± 13 and 59 ± 12 mg/dl; and low-density lipoprotein (LDL)-cholesterol, 87 ± 24 and 90 ± 25 mg/dl. The mean TC across all age groups ranged from 149 to 172 mg/dl for boys and 157 to 170 mg/dl for girls. In boys, the TC concentration was highest at age 11 (172 mg/dl), and in girls was highest at age 7 (170 mg/dl). Borderline hypercholesterolemia (TC > 170 mg/dl)was found in 36.5% of boys (13.5-53.1%) and 39.7% of the girls (28.3-48.6%). Hypercholesterolemia (TC > 200 mg/dl) was found in 9.7% of males (3.1-16.6%) and 10.3% of the females (5.0-14.9%). Conclusions: The prevalence of borderline bypercholesterolemia was 38.0% for TC and 17.2% for LDL-C, and for hypercholesterolemia, it was 9.9% for TC and 5.8% for LDL-C. The higher TC levels in Taiwanese children were primarily due to higher HDL-C and TG levels. |
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