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題 名 | Distribution of Sensitive Loci Where Localized Twitch Response can be Elicited in Rat Skeletal Muscle=大白鼠骨骼肌中可誘發局部抽搐反應部位之分佈 |
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作 者 | 張育彰; 高聖芬; 官大紳; 洪章仁; | 書刊名 | 復健醫學會雜誌 |
卷 期 | 26:1 1998.03[民87.03] |
頁 次 | 頁1-8 |
分類號 | 418.92 |
關鍵詞 | 肌筋膜引痛點; 大白鼠; 骨骼肌; 肌肉抽搐; Myofascial trigger point; Rat; Skeletal muscle; Muscle twitch; |
語 文 | 英文(English) |
中文摘要 | 臨床上,肌筋膜引痛點(myofascial trigger point)是相當常見的肌肉疼痛問題。當引痛點受到刺激時(如針刺、指頭按捏),則會引發局部抽搐反應(local twitch response),此亦為引痛點的特徵。近來的研究顯示,引痛點乃位於神經肌肉交界符之終板帶(endplate zone)。本實驗的目的即在藉由大白鼠骨骼肌中敏感小點(sensitive loci)的分佈,來看引痛點是否集中於終板帶。總計本實驗共使用了39隻大白鼠,麻醉後在兩側的股二頭肌(biceps feroris)繃緊肌帶(taut band)上,經由閾值(threshold current)電流0.5-1.0毫安培定出終板(endplate sites)位置。再以終板區為基準,每一公釐為一軌,軌上每隔一公釐便以針頭快速垂直刺入肌肉,以觀察是否有局部抽搐反應。結果顯示,雖然有部皆的局部抽搐反應分佈於周圍,但多數的局部抽搐反應則集中於社經肌肉交界處附近,且有統計學上的意義。此結果更支持引痛點與不正常之終板有關的假說。 |
英文摘要 | Myofasicial trigger point (MTrP) is a quite common painful muscular disorder in clinical practice. When an MTrP is mechanically stimulated (needling or snapping palpation), a local twitch response (LTR) can be elicited, which is one of the characteristics of MTrP. Recent studies on humans and rabbits suggest that an MTrP is at the endplate zone. The purpose of this study is to map the sistribution of sensitive loci from which an LTR can be elicited by mechanical stimulation of it in rat skeletal muscle. A total of 39 sprague-Dawley rats were studied in this experiment. After general anesthesia, the biceps femoris was exposed, and electrical stimulation with a threshold current of 0.5-1.0 mA was applied to identify the endplate zone. Nice to thirteen tracks (1 mm part between tracks) were explored for each muscle. For each track, every 1 mm was an investigating site. To elicit LTRs, the needle was rapidly inserted perpendicularly into the muscle. It was found that, although some sensitive loci were distributed in the periphery, most of the sensitive loci were concentrated in the endplate zones, with statistical significance. This finding may further support the hypothesis the MTrPs are related to abnormal endplates. |
本系統中英文摘要資訊取自各篇刊載內容。