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頁籤選單縮合
題 名 | Alcohol Preference Genetics in the House Mouse=小家鼠之酒精偏好遺傳 |
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作 者 | Derr,Rachel L.; Peirce,Jeremy L.; Silver,Lee M.; | 書刊名 | 動物研究學刊 |
卷 期 | 37:1 1998.01[民87.01] |
頁 次 | 頁31-38 |
分類號 | 415.121 |
關鍵詞 | 乙醇; 小家鼠; 雙瓶選擇; C57BL/6; DBA/2; Ethanol; C57BL/6; DBA/2; Mice; 2-bottle choice; |
語 文 | 英文(English) |
中文摘要 | 好幾個小家鼠的近親交配品系顯示品系內穩定但品系間差異很大的酒精攝取量。 大部份品系的酒精攝取量屬中等,但C57BL/6品系的老鼠攝取大量的酒精,而DBA/2品系 的老鼠攝取微量的酒精。和這個表型有關的基因座,一個位於第二對染色體上,另有一個位 於第十一對染色體上。本文闡述這個研究的進展以及我們對於發現的基因座進行高解析度基 因定位和分析的策略。 |
英文摘要 | Rachel L. Derr, Jeremy L. Peirce and Lee M. Silver (1998) Alcohol preference genetics in the house mouse. Zoologial Studies 37 (1): 31-38. Various strains of inbred mice show strain-specific and widely varying levels of alcohol consumption. Most strains consume moderate levels of ethanol; however, C57BL/6 mice consume ethanol at very high levels and DBA/2 mice consume ethanol at very low levels. We have mapped several loci, 1 located on chromosome 2 and 1 on chromosome 11, which are involved in this phenotype. We outline here the progress of this research and our strategy for higher-resolution mapping and analysis of the loci discovered. |
本系統中英文摘要資訊取自各篇刊載內容。