頁籤選單縮合
題名 | 免疫調節方劑之研究(2)--補陰方劑=Studies on Immunoregulation of Chinese Prescription(Ⅱ)--Replenishing the Vital Essence Prescription |
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作者 | 梁文俐; 楊玲玲; Liang, Wen-lee; Yang, Ling-ling; |
期刊 | 臺灣科學 |
出版日期 | 19971200 |
卷期 | 50:2 1997.12[民86.12] |
頁次 | 頁16-29 |
分類號 | 413.4 |
語文 | chi |
關鍵詞 | 中藥方劑; 免疫系統; 抗體力價; T淋巴細胞及其亞群細胞; 協助性T細胞/抑制性T細胞比值; Chinese prescriptions; Immunity system; Antibody titer; T lymphocyte and subclass of T cells; Th/Ts ratio; |
中文摘要 | 在免疫調節方劑之研究I提到中人體正氣被病邪削減或抑制之結果所致,因此正氣 之強弱乃決定於疾病之發生與否?中國醫學中治療疾病用藥有所謂之『扶正法邪』法則,即 針對此而發, 真有『扶正袪邪』作用之藥物,因此在本報告繼續選擇〞中藥補益〞方劑 -- 天王補心丹、百合固金湯、八味地黃丸,六味地黃丸等四個補陰方劑,利用血球凝集試驗法 以及直接螢光染色法,分別觀察實驗動物之抗體力價,T 淋巴細胞及其亞群細胞,協助性 T 細胞╱抑制性 T 細胞 (Th/Ts) 比值之變化。實驗結果,顯示補益方劑對正常實驗老鼠並無 明顯影響, 但治療組 (以 prednisolone 引發免疫低下 ) 中以知柏八味地黃丸顯示真有免 疫提升功能,所呈現效能與免疫增強劑 levamisole 相似,對免疫低下之預防亦普逼真有提 升作用•且效果較 levamisole 強。 |
英文摘要 | The traditional Chinese medicine have been known involved in immunological effect. The traditional Chinese medical science has held by "disease is confrontation between vital energy of the human body and pathogenic factors", therefore disease cause is usually decided by genuine energy which not balance. Generally, Chinese medicine therapy rule is "to strengthen the patient's resistance and dispel the invading pathogenic factors (扶正袪邪 ) in order to action on immune disease". We chose 4 Tonic Chinese prescriptions: Tian Wang Bu Xin Dan, Bai-He Gu Jin Tang, Ba Wei Di-Hung Wan, Liu Wei Di-Hung Wan, Which are used in the trcatment of deficiency of many abnormal genuine energy functional activities by Chinese medical doctor. Combination of direct agglutination test micro-hemagglutination method and direct fluorescent antibody test Fascan Flow Cyto-mete, to detect Antibody titer, T lymphocyte and subclass of T cells (helper T cell, suppressor T cell) and Th/Ts ratio. Ther result have found (1) that those prescription was not affected to mice on normal condition, (2) it had good immuno-enhance activity when prednisolone induced immunosuppressed condition as well as immunopotentiator (levamisole) results by giving three different prescription of Ba Wei Di-Hung Wan, (3) in precaution test we found more than half tonic medicine prescription had better activity than levamisole treatment. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。