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頁籤選單縮合
題名 | Blood Groups and Transfusion Medicine in Taiwan=臺灣人的血型 |
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作者 | 林媽利; | 書刊名 | 臺灣醫學會雜誌 |
卷期 | 96:12 1997.12[民86.12] |
頁次 | 頁933-942 |
分類號 | 414.7 |
關鍵詞 | 臺灣人; 血型; Blood groups; Para-Bombay phenotype; Lewis phenotype; MiIII phenotype; Transfusion medicine; |
語文 | 英文(English) |
英文摘要 | There are significant differences in the frequencies of various blood group antigens between Taiwanese and Caucasians, and also in the frequencies of the corresponding alloantibodies. The most interesting discoveries concerning Taiwanese are: 1)The most common ABO subgroups are the B �� phenotype, followed by the A phenotype. 2)The secretory H-deficient para-Bombay phenotype (O), which results from mutations in five different h genes, is not uncommon. 3)The Le (a+b+) phenotype has a frequency of about 25% and the Le(a+b-) phenotype is absent except in a few of the indigenous groups. 4)Anti-`Mi' is the most common clinically significant alloantibody causing intravascular hemolytic transfusion reactions and hemolytic disease of the newborn. 5)the incidence of the corresponding MiIII blood group phenotype varies among the different ethnic groups, ranging from 0% among descendants of mainland Chinese from north of the Yangste to 88.4% among the Ami tribe. 6)There is an almost complete absence of Di and St antigens among the indigenous populations, in contrast to incidences of greater than 2% among the Chinese ethnic groups. 7)Nearly all (99.67%) Taiwanese are positive for the Rh(D) antigen. Among those with Rh(D) negative phenotype, about 30% have a very weak Rh(D) positive phenotype (D phenotype). Since the corresponding anti-D antibody is also rarely encountered, routine D typing is not necessary. 8)Some rare blood group phenotypes found in Taiwanese are the i phenotype associated with congenital cataract, D phenotype, Dc-phenotype, Jk(a-b-) phenotype, and Lu(a-b-) phenotype. |
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