查詢結果分析
來源資料
相關文獻
- 不同嚴重程度滅壓病之血小板數目的變化
- Cytokines and Growth Factors Secreted by Vero Cells Destined for Embryo Cocultures
- 新生兒異族免疫性血小板低下症
- Different Densities of Human Eosinophils Respond Differently to PAF and IL-5
- Idiopathic Thrombocytopenic Purpura Preceding Malignant Lymphoma: Report of One Case
- Synthesis and Antiplatelet Activity of 5-Methyl-2-Furyl Methyl Ketone Phenylhydrazones and Related Compounds
- Synthesis and Antiplatelet Activity of 1,3-Disubstituted 5-Methylthieno[3,2-c]Pyrazoles
- 誘導血小板聚集觀察腦中風
- 九節木之活血化瘀活性分析
- 紅斑性狼瘡合併血小板缺乏病例討論
頁籤選單縮合
題 名 | 不同嚴重程度滅壓病之血小板數目的變化=Changes of Platelet Count under Different Severities of Decompression Sickness |
---|---|
作 者 | 林政彥; 劉可威; 張陸澎; 林自強; 李惠傑; | 書刊名 | 中華職業醫學雜誌 |
卷 期 | 4:1 1997.01[民86.01] |
頁 次 | 頁37-43 |
分類號 | 412.85 |
關鍵詞 | 滅壓病; 血小板; 水底時間; |
語 文 | 中文(Chinese) |
中文摘要 | 氣泡是產生減壓病(decompression sickness)的直接及主要病因。許多研究顯示 有減壓病之潛水者血中血小板數目 (platelet count) 明顯減少 [1,2,3,4,5]。本研究旨在 探討血液中血小板數目變化與減壓病之嚴重程度是否有相關性。本研究採用 50 隻雄性天竺 鼠,體重 580 ± 41.8 公克,按隨機抽樣法分成每 10 隻一組。 每組置於動物高壓艙中, 以空氣加壓至九大氣壓,分別停留 10、20、30、40 或 50 分鐘後再減壓,加壓及減壓之速 率皆為每分鐘二大氣壓。 在實驗前後,分別抽取天竺鼠靜脈血 0.9 毫升,以自動血液分析 儀分析血液中血小板數目。 此外, 經減壓後在天竺鼠胸前以都卜勒超音波氣泡探測器( Doppler ultrasonic bubble detector )偵測氣泡有無產生。 最後,將減壓後之天竺鼠依 減壓病之臨床症狀重新分組,分為沒有減壓病症狀,下身麻痺( paraplegia )及死亡三組 。結果發現:1. 經減壓後在天竺鼠胸前皆可偵測到有氣泡產生;2. 經減壓後血液中血小板 數目減少; 3. 血小板數目減少比率的程度與水底時間( bottom time )成正比;4. 減壓 病之臨床症狀愈嚴重,血小板數目減少比率愈多。從上述所得結果,我們認為血中血小板數 目變化與減壓病之嚴重程度是有正相關性,且可利用此變化值作為減壓病診斷評估之重要實 驗指標。 |
英文摘要 | Bubble formation is the direct and principal etiological factor in the development of decompression sickness ( DCS ). Many studies showed that DCS is accompanied by a reduction platelet count. This report is to study the correlative changes of platelet count with different severities of DCS. Fifty male guinea pigs, 580 ± 41.8 grams in weight, were subjected to a simulated air-dive profile of 9 ATA for 10 min, 20 min, 30 min, 40 min or 50 min with ten animals each. The descent and ascent rates were at 2 ATA/min. Both before and after dive, 0.9 ml venous blood was taken and mixed in a EDTA test tube. The platelet count was measured by a cell counter. The bubble signals were detected over precordium with a Doppler ultrasonic bubble detector after dive. The clinical manifestations were observed and classified into three groups: no signs of DCS, paraplegia and death. All subjects showed positive findings of bubble signal after dive. There is a significant decrease of platelet count after all decompression profiles. There is a linear regression between the ratio change of platelet count and the bottom time of decompression profile. There is a positive correlation between ratio changes of platelet count and severities of DCS. This results suggest the measurement of platelet count seemed to provide a clinical index both for the laboratory diagnosis of DCS and the evaluation of severlities of DCS. |
本系統中英文摘要資訊取自各篇刊載內容。