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頁籤選單縮合
題名 | Carcinoembryonic Antigen in Breast Cancer=乳癌之癌胚胎抗原 |
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作者姓名(中文) | 施伯安; | 書刊名 | 中華民國外科醫學會雜誌 |
卷期 | 26:2 民82.03-04 |
頁次 | 頁1655-1661 |
分類號 | 415.138 |
關鍵詞 | 乳癌; 癌胚胎抗原; Carcinoembryonic antigen(CEA); Breast cancer; |
語文 | 英文(English) |
中文摘要 | 癌胚胎抗原是一種被廣泛運用於胃腸道癌症的腫瘤指標。對於其他部位的腫瘤,它在臨床上的運用仍不甚清楚。本篇主要是針對乳癌的患者,以組織癌胚胎抗原檢查及連續性的血清癌胚胎抗原檢查,作追踪治療。結果發現:對於早期乳癌,術前的血清癌胚胎抗原檢查,並無法預期其預後的好壞。術後的追踪,也只有20.7%的患者,能夠早期的偵測到復發。 但對於末期乳癌,66%的患者,其血清癌胚胎抗原值都會增高,尤其是轉移到肝臟時。且若經過化學及賀爾蒙治療後,其血清癌胚胎抗原值仍然沒有下降,則一般預後都很差。 至於組織癌胚胎抗原及血清癌胚胎抗原的關連性,到目前仍不甚清楚。但一般而言,當患者的血清癌胚胎抗原增高時,其組織癌胚胎抗原都呈現陽性反應。而且若有異常的血清癌胚胎抗原合併陽性的組織癌胚胎抗原,那預後都較差。 |
英文摘要 | Carcinoembryonic antigen (CEA) is widely used as a tumor marker for gastrointestinal neoplasms. Its role in the management of other tumors is poorly defined. A prospective study of tissue carcinoembryonic antigen (T -CEA) and serial plasma carcinoembryonic antigen (P-CEA) values in patients with breast cancer has been undertaken. Plasma carcinoembryonic antigen is of no prospective value in primary operable breast cancer; in follow-up, serial measurements can predict recurrence, but in only 20.7%. Of patients with an advanced stage of breast cancer, 66% will have elevated P-CEA level, especially involving the bone or liver. If P-CEA elevation persists, in spite of chemohormonal therapy, prognosis is poor. The relationship between T-CEA and P-CEA is not well-established. In patients with an elevated P-CEA level, and a strongly positive T-CEA, the prognosis is poorer than for others. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。