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題名 | 新生兒B群鏈球菌感染症 |
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作者 | 高信安; 黃富源; 徐世達; | 書刊名 | 中華民國小兒科醫學會雜誌 |
卷期 | 27:3 民75.05-06 |
頁次 | 頁240-245 |
分類號 | 417.517 |
關鍵詞 | 新生兒; B群鏈球菌感染症; |
語文 | 中文(Chinese) |
中文摘要 | 本文收集馬偕紀念醫院最近5年來罹患B羣溶血性鏈球菌(group B,β-hemolytic streptococci, GBS)或染之新生兒病例共計26例。其中早發型表現者有13例約為血液培養陽性之新生兒敗血症,早產兒佔5例,發病年齡在24小時內者有10例。臨床症狀以發紺、呼吸急促類似新生兒呼吸窘迫症狀羣者佔大部份。胸部X光檢查大多不正常,其中以肺炎最多,吸入性肺炎次之。有1例早產兒其臨床症狀及胸部X光檢查發現與玻璃樣膜疾病無法區別。死亡有6例,佔46%。另外遲發型表現者有13例,共中12例均為新生兒腦膜炎。發病平均年齡為23天,臨床主要症狀為發燒、拒食、痙孿。11例接受2至4星期住院抗生素治療,追蹤結果7例無明顯的神經後遺症,1例水腦症,3例失去聯絡,另外2例自動出院病人皆死亡。 |
英文摘要 | Twenty-six cases of group B β-hemolytic streptococcal (GBS) infection were seen at Mackay Memorial Hospital from 1980 to 1984. Thirteen cases of early-onset GBS infection were neonatal sepsis with fulminant course. Most occurred within 24 hours of life, presenting with cyanosis and tachypnea. Chest radiographic findings always revealed pneumonia or aspiration pneumonia. In one premature baby, the clinical features and chest radiograph were undistinguishable from hyaline membrane disease. There were six cases of mortality. Factors related to mortality were apnea, hypoxemia. bradycardia and positive culture of both blood and CSF. Twelve of thirteen cases of late onset GBS infection were neonatal meningitis. The average age at onset was 23. days. The predominent symptoms were fever, poor feeding and seizures. Two cases, were, discharged against, advice and finally expired. Eleven treated and survival cases were followed up at least one year after discharge. Seven cases showed no obvious neurologic sequelae, one case had hydrocephalus and three cases were lost to follow up. |
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