頁籤選單縮合
題名 | 2018年中部地區某家庭多重抗藥性結核病衍生校園及非同住者聚集事件調查=Investigation of a Multi-Drug Resistant Tuberculosis Cluster in a Family and Campus, Central Taiwan, 2018 |
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作者姓名(中文) | 陳鈺欣; 林巧雯; 王功錦; 蔡韶慧; 柯靜芬; 吳智文; | 書刊名 | 疫情報導 |
卷期 | 39:6 2023.03.21[民112.03.21] |
頁次 | 頁83-88 |
分類號 | 412.42 |
關鍵詞 | 多重抗藥性結核病; 聚集事件; 多重抗藥性結核病個案接觸者之潛伏結核感染治療; Multiple drug resistance tuberculosis; MDR-TB; Cluster; Treatment of latent tuberculosis infection in contacts with multiple drug resistance tuberculosis; MDR-LTBI; |
語文 | 中文(Chinese) |
DOI引用網址 | 10.6524/EB.202303_39(6).0002 |
中文摘要 | 2018年中部地區某家庭多重抗藥性結核病聚集事件,家庭同住5名中,共通報確診4名,且經疾病管制署分枝桿菌實驗室基因比對,均為同型別菌株。指標個案於2018年11月因症就醫通報確診後,展開接觸者調查,找出家庭接觸者轉個案2名,隔年追蹤再新增1名家庭接觸者轉個案。此外,家庭以外接觸者在後續追蹤過程,也被陸續通報確診,其中2名為同型別菌株MDR個案,另1名無細菌學證據。本事件經接觸者檢查衛教,有效找出其他個案,其中1名發病之接觸者前於2017年職場體檢異常,卻未積極追蹤,建議應建立體檢異常回報追蹤機制。另外,應鼓勵加入多重抗藥性結核病個案接觸者之潛伏結核感染治療計畫,以降低接觸者發病風險。 |
英文摘要 | In 2018, a family cluster of multi-drug resistant tuberculosis (MDR-TB) occurred in central Taiwan. Among the 5 family members, 4 were diagnosed with MDR-TB. The isolates were sent to the Mycobacterium Laboratory at Center for Research, Diagnostics and Vaccine Development for genotyping, and the results showed the same genotype. The index case went to a hospital due to a persistent cough in November 2018 and was diagnosed with pulmonary tuberculosis. We conducted a contact investigation immediately, and two household contacts were diagnosed with MDR-TB. One more household contact developed MDR-TB one year later during follow-up. In addition to household contacts, two other contacts were diagnosed with MDR-TB. One contact had the same genotype isolate, and the other one had no culture report. Through our contact investigation and health education, we found cases more efficiently. We suspected one of these cases was the primary case because the case had an abnormal chest X-ray report in 2017, but he did not seek medical advice. We recommend establishing a reporting system for abnormal physical examinations. Besides, we also recommend encouraging contacts to receive latent tuberculosis infection treatment to lower the risk of becoming an active MDR-TB case. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。