查詢結果分析
相關文獻
- 2015年臺灣桿菌性痢疾流行病學與抗藥性分析
- 苗栗縣B群X變異型桿菌性痢疾群突發事件
- Visualization of Chromosome-Sized DNA Molecules by using PFGE for Yeasts Isolated from Infectious Fresh Water Prawn (Macrobrachium rosenbergii de Mann) in Taiwan
- 談桿菌性痢疾之防治經驗
- Investigation of an Outbreak of Pseudomonas Putida Using Antimicrobial Susceptibility Patterns, Pulsed-Field Gel Electrophoresis of Genomic DNA and Restriction Fragment Length Polymorphism of PCR-Amplified rRNA Operons
- Characterization of Group D1 Non-typhoid Salmonella Isolates by Serotyping and Pulsed Field Gel Electrophoresis
- 桿菌性痢疾(Bacillary Dysentery)
- An Outbreak Report of Shigellosis in Taipei County
- DNA Polymorphism of Mycobacterium Abscessus Analyzed by Infrequent-Restriction-Site Polymerase Chain Reaction
- 腫瘤藥物敏感性試驗(1)--腫瘤細胞分離與培養
頁籤選單縮合
題名 | 2015年臺灣桿菌性痢疾流行病學與抗藥性分析=Epidemiology and Drug Resistance of Shigellosis, Taiwan, 2015 |
---|---|
作者姓名(中文) | 廖盈淑; 廖春杏; 梁綉雲; 王佑文; 曹其森; 邱乾順; | 書刊名 | 疫情報導 |
卷期 | 33:4 2017.02.21[民106.02.21] |
頁次 | 頁24-25+61-70 |
分類號 | 415.133 |
關鍵詞 | 桿菌性痢疾; 脈衝式電泳; 藥物敏感性試驗; Shigellosis; Pulse-field gel electrophoresis; Antimicrobial susceptibility testing; Ciprofloxacin; Azithromycin; |
語文 | 中文(Chinese) |
中文摘要 | 2015年國內出現186例桿菌性痢疾病例,境外移入病例占56.5%,實驗室取得147株菌株,當中Shigella sonnei、S. flexneri與S. boydii分占58.5%(86株)、38.8% (57株)與2.7%(4株);S. sonnei來源有29.1%(25)病例為印尼與越南勞工,70.9% (61)病例是本國籍,當中有14人可能在境外感染;S. flexneri來源有68.4% (39)病例為印尼籍勞工,18個本國籍病例有4人有國外旅遊史。S. boydii菌株來源為印尼籍或具有印尼旅遊史的病例。藥物敏感性試驗檢測78株S. sonnei菌株,47株呈現ciprofloxacin抗藥性,來源皆為本國籍,有11人發病潛伏期間曾到中國、日本、越南、印尼或柬埔寨旅遊;ciprofloxacin抗藥菌株來源有31人為HIV帶原,皆為男性,年齡介於20–46歲(平均31.4歲),有2人發病前曾到過中國與日本旅遊。6月開始出現S. flexneri血清型3a的流行,全年9個病例皆無國外旅遊史的本國人,年齡22–44歲(平均33.3歲)之男性,其中6人為HIV感染者,菌株皆具同一PFGE基因型別,有8株菌株具azithromycin抗藥性。Ciprofloxacin與azithromycin是桿菌性痢疾的主要指引用藥,過去抗藥菌株在國內相當罕見,2015年出現高比率的ciprofloxacin抗藥菌株與首度發現azithromycin抗藥菌株,而抗藥菌株主要在男男戀社群中流行;未來需加強痢疾桿菌之藥敏試驗,以提供用藥參考,並加強特定社群的衛生宣導,防止抗藥菌株之傳播感染。 |
英文摘要 | A total of 186 shigellosis cases were reported in 2015 and 56.5% of which were imported. Of the 147 isolates collected in the year by the Central Regional Laboratory of Taiwan Centers for Disease Control, 86 isolates (58.5%) were Shigella sonnei, 57 (38.8%) were S. flexneri and 4 (2.7%) were S. boydii, respectively. Among the 86 S. sonnei isolates, 25 (29.1%) were recovered from immigrant workers from Indonesia and Vietnam, and 61 (70.1%) were Taiwanese of whom 14 acquired the infections during traveling abroad. Of the 57 S. flexneri isolates, 39 (68.4%) were recovered from Indonesian immigrant workers and 18 were Taiwanese of whom 4 had travel history abroad. The 4 S. boydii isolates were recovered from Indonesian workers and with travel history to Indonesia. Antimicrobial susceptibility testing revealed that 47 of 78 S. sonnei isolates tested were ciprofloxacin-resistant. All the ciprofloxacin-resistant isolates were recovered from Taiwanese among whom 11 had travel history to China, Japan, Vietnam, Indonesia and Cambodia, and 31 were HIV-infected. All the cases with HIV infection were male of 20–46 (average 31.4) year-old and 2 cases had traveled to China and Japan during the incubation period. The first S. flexneri 3a infected case emerged in June. Nine S. flexneri 3a infected cases were found in 2015; they were Taiwanese, male, 22–44 years-old (average 33.3), and 6 were HIV-infected. All S. flexneri 3a isolates belonged to a common PFGE genotype and all but one were resistant to azithromycin. Ciprofloxacin and azithromycin are the recommended treatment drugs for shigellosis in Taiwan. In the past, Shigella strains resistant to these two drugs were infrequently detected but, in 2015, Shigella strains with ciprofloxacin resistance had become prevalent and azithromycin resistance had emerged. The resistant strains were primarily circulated among the men who have sex with men (MSM). We suggest that public health authorities have to routinely perform antimicrobial susceptibility testing on Shigella isolates for the treatment of Shigella infections and strengthen hygiene education among MSM to halter the spread of ciprofloxacin- and azithromycin-resistant strains. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。