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頁籤選單縮合
題名 | A Young Adult Woman with Severe Osteoporosis due to Cushing's Disease: A Case Report and Literatures Review=一位年輕成年女性罹患因庫欣氏病所導致的嚴重骨鬆骨折:病例報告與文獻回顧 |
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作者 | 李晏榮; 蔡之祐; 薛純; 林承緯; 陳思達; 林仁德; 黃兆山; | 書刊名 | 內科學誌 |
卷期 | 27:5 2016.10[民105.10] |
頁次 | 頁267-273 |
分類號 | 415.934 |
關鍵詞 | 庫欣氏病; 骨鬆骨折; 骨質疏鬆症; Cushing's disease; Low trauma fracture; Osteoporosis; Premenopausal woman; |
語文 | 英文(English) |
中文摘要 | 在臨床上大多數的庫欣氏症是導因於醫源性類固醇的使用,而長期使用類固醇會導致骨質疏鬆症的發生進而併發骨鬆性骨折。內生性的類固醇過多症併繼發性的骨鬆骨折在臨床上相對罕見,因此今天我們報告一例35歲年輕女性因為庫欣氏病而導致嚴重骨鬆的病人,希望我們的診斷與治療經驗能提醒各位臨床醫師。 |
英文摘要 | In patients with Cushing's syndrome, the most common cause is iatrogenically excessive use of glucocorticoids. The second most common form is Cushing's disease. Glucocorticoids have a direct effect on bone, causing inhibition of bone formation and enhancing bone resorption. Glucocorticoid-induced osteoporosis (GIOP) is one of the most important side effects of glucocorticoid use, as it could result in an increased risk of fractures. However, severe osteoporosis due to endogenous hypercortisolism was relatively uncommon in the clinical setting, especially for a young adult woman. Therefore, we present a case of a 35-year-old premenopausal woman with Cushing's disease who presented with a low trauma fracture. We hope that our experience of this case will remind doctors to be aware of this unusual complication of Cushing's disease. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。