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題名 | 運用田口式最佳化法評量99mTc-MDP之骨頭造影參數設定=Optimization the 99mTc-MDP Bone Scan Imaging System Using the Taguchi Analysis |
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作者姓名(中文) | 陳俊吉; 葉大銘; 李永康; 潘榕光; | 書刊名 | 中華放射線技術學雜誌 |
卷期 | 36:2 2012.06[民101.06] |
頁次 | 頁75-82 |
分類號 | 416.261 |
關鍵詞 | 壓克力假體; 田口實驗設計法; 變異數分析; 99mTc-MDP; Phantom; Taguchi; ANOVA; |
語文 | 中文(Chinese) |
中文摘要 | 運用田口式最佳化法評量99mTc-MDP之骨頭造影參數設定。對於同位素影像品質最佳化設定,有鑑於各廠家所推鑑設定造影參數條件不同,考量於前人針對全身骨頭掃描病人影像,在掃描速度都只建議值10~15 cm/min,較少真正應用於臨床探討。本實驗應用gamma-camera E CAM(上標 +) coincidence siemens USA,以自製的壓克力假體(大小為20×30×2 立方公分、表面有5mm深、1 mm寬的雷射刻痕),應用田口品質實驗設計法(Taguchi methods),採用L9(3^4)直交表設計掃描27次,影像結果由三位服務五年以上放射師評分,而得到的最佳化設定結果,應用於臨床驗證5位全身骨頭掃描病人影像,應用西門子(E.CAM(上標 +);ICON)軟體,測量骨骼與組織比(ROI),再經由核子醫學科專科醫師作影像品質作評比。結果由評分資料分析與變異數分析(ANOVA),考慮臨床應用條件修正,得到一組最佳化參數組合為:使用低能量高解析度的準直儀(LEHR),掃描速度16 cm/min,同位素藥物99mTc-MDP 18 mCi,離體距離採2 cm,電腦像素256×1024。結論利用自製假體,運用田口方法,可節省實驗的組數,節省實驗的時間,而能得到的影響因子,將本實驗結果再運用於臨床驗證,才能得最佳且理想能運用於臨床上的條件,值得推薦同業參考運用。 |
英文摘要 | The optimization of the 99mTc-MDP Bone scan imaging system was accomplished using the Taguchi analysis in this study. The E CAM(superscript +) coincidence siemens USA gamma camera and an indigenous acrylic (Poly methyl metharylate: PMMA) phantom (20×30×2 cm^3, with a 5mm deep, 1 mm wide laser notch on the surface) was adopted in this study to conform the orthogonal array that was recommended by the Taguchi. The quality of images was graded by 3 Radiological Technologists who service more than 5 years. A set of optimal parameters combination was determined, and then verified to clinical whole body bone scans of 5 patients. We use the software (ICON) in the E.CAM(superscript +) Coincidence, Siemens, USA to measure the bone to tissue ratio (ROI). The quality of whole body bone scan images were graded by 3 nuclear medicine specialized physician. The final optimal parameters combination is based on the result of grading data analysis of variance (ANOVA), and correlated to the clinical conditions. The final optimal parameters combination is as follows:low-energy high-resolution collimator (LEHR), scanning speed 16 cm/min, Tc-99m MDP 18mCi, the distance to body is determined 2 cm and the obtained image in a 256×1024 matrix. The application of Taguchi method can effectively suppress the number of experimental groups. We verify the experimental results in the clinical examinations, and achieve high agreement in real examinations. The Taguchi analysis is also helpful to other Radiological Technologists in handling the clinical studies. |
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