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題 名 | Concomitant Primary Lung Cancer and Metastatic Pulmonary Colorectal Cancer That Responded to Gemcitabine/Cisplatin/Bevacizumab Combination Therapy=併存原發性肺癌及轉移性結腸直腸癌在接受Gemcitabine/Cisplatin/Bevacizumab治療後獲得改善 |
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作 者 | 陳鴻明; 潘競成; 蔡俊明; 許文虎; 楊純豪; 顏厥全; | 書刊名 | 臺灣癌症醫學雜誌 |
卷 期 | 2:1 2015.03[民104.03] |
頁 次 | 頁76-82 |
分類號 | 418.31 |
關鍵詞 | 結腸直腸癌; 雙重惡性腫瘤; 肺癌; Bevacizumab; Colorectal cancer; Double primary cancer; Gemcitabine; Lung cancer; |
語 文 | 英文(English) |
中文摘要 | 結腸直腸癌相關之雙重惡性腫瘤發生率約為百分之一至六,而同時產生結腸直腸癌及另一原發性惡性腫瘤的發生率更是少於百分之一,其中同時合併原發結腸直腸癌以及肺癌約為百分之零點一。在這篇文章裡,我們呈現一位罕見病例同時產生原發性肺癌以及肺部轉移性結腸直腸癌;起初腫瘤位於肺部右上葉及右下葉,在經過 gemcitabine/ cisplatin/bevacizumab合併之化學治療後,右上葉腫瘤為穩定狀態而右下葉腫瘤明顯縮小,術後切片證實右下葉腫瘤為轉移性腺癌,並經結腸鏡檢查證實為直腸癌合併肺轉移。病患接受原發直腸癌切除術併化學治療後,超過兩年仍無病存活。 |
英文摘要 | The incidence of double primary malignancy in colorectal cancer is rare (approximately 1-6%), and synchronous double primary malignancy is even rarer for cases involving colorectal cancer. Indeed, its incidence is estimated to be less than 1%. The probability of concurrent colorectal cancer and lung cancer, in particular, is extremely low (approximately 0.1%). In this report, we present such a case of synchronous primary lung cancer and pulmonary metastatic colorectal cancer, which was mistaken for primary lung cancer with lung-to-lung metastasis. Tumors were identified in the upper and lower lobes of right lung. After the patient received a lung cancer chemotherapy, gemcitabine/cisplatin/bevacizumab, the right upper lobe tumor was stable in size, and the right lower lobe tumor regressed. Surprisingly, the right lower lobe tumor was proven to be metastatic colorectal cancer after surgical resection. A primary rectal tumor was then identified through colonoscopy. Subsequently, the patient underwent surgical resection of the primary rectal cancer and chemotherapy. She has now remained disease-free for more than two years. |
本系統中英文摘要資訊取自各篇刊載內容。