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題名 | The Antimutagenic Properties of Seaweed Oligosaccharides, Evaluated Using Salmonella typhimurium TA98=以Salmonella typhimurium TA98評估海藻寡醣之抗致突變性 |
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作 者 | 吳紹祺; 潘崇良; | 書刊名 | 臺灣水產學會刊 |
卷期 | 39:2 2012.06[民101.06] |
頁次 | 頁115-126 |
分類號 | 346.217 |
關鍵詞 | 洋菜酶; 抗致突變性; 海藻寡醣; Agarases; Antimutagenicity; Seaweed oligosaccharides; |
語文 | 英文(English) |
中文摘要 | 無論使用直接型(4-NQO)致突變劑或間接型致突變劑(B[a]P)誘導Salm. typhimurium TA98之抗致突變性,以紫菜萃取多糖在十種海藻萃取多醣中具有最佳表現,且與其多酚類含量有關。在直接型致突變劑下,60種藻類寡醣水解物對4NQO所具抗致突變率在12-94%間。在間接型致突變劑,60種藻類寡醣水解物對B[a]P所具抗致突變率在18-89%間。以MAEF-108 agarases分解所得紫菜寡糖經劃分後,證明其所具抗致突變率主要來自多酚類,而新洋菜二糖亦有次要貢獻。 |
英文摘要 | Porphyra (Por.) dentate of ten seaweed polysaccharide extracts (SPEs) have the greatest antimutagenic effect on Salmonella (Sal.) typhimurium TA98 under the direct action of the mutagen, 4-NQO; and the indirect action of mutagens, B[a]P. The antimutagenic effects of ten SPEs were related to their polyphenol contents. Under the influence of the directly acting mutagen, 4-NQO, the antimutagenic effects on 60 SOLs were shown to range from 12 to 94%. Under the influence of indirectly acting mutagens B[a]P, the antimutagenic effects on 60 SOLs were from 18 to 89%. The antimutagenic effects of different fractionations from SPE of Por. dentate digestive, by MAEF-108 agarases, demonstrated not only a major contribution from polyphenols, but also a minor contribution from neoagarobiose. |
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