查詢結果分析
相關文獻
- The Association of Stroke and Family History of Stroke Depends on Its Subtypes and Gender: A Family History Study in Taiwan
- 腦中風患者吞嚥功能臨床評估可靠性之探討
- 上矢狀竇栓塞併雙側偏癱:病例報告
- 運動後低血壓反應與血壓控制之探討
- The Effect of Sphenopalatine Postganglionic Neurotomy on the Alteration of Local Cerebral Blood Flow of Normotensive and Hypertensive Rats in Acute Cold Stress
- 以動脈注射血栓溶劑治療急性缺血性腦中風:七例報告
- 成功使用血栓溶解劑治療急性缺血性腦中風:一病例報告暨文獻回顧
- 臺北市機構式長期照護體系之腦中風物理治療服務需求調查
- 糖尿病與腦中風
- The Influence of Rehabilitation Therapy on the Prognosis for Stroke Patients--A Preliminary Study
頁籤選單縮合
題 名 | The Association of Stroke and Family History of Stroke Depends on Its Subtypes and Gender: A Family History Study in Taiwan=腦中風與其中風家族史之關聯性隨腦中風型態與性別而異 |
---|---|
作 者 | 徐文俊; 陳獻宗; 吳逸如; 張宏旭; 呂榮國; 羅榮昇; | 書刊名 | Acta Neurologica Taiwanica |
卷 期 | 18:3 2009.09[民98.09] |
頁 次 | 頁161-169 |
分類號 | 415.922 |
關鍵詞 | 腦中風; 家族史; Cerebral hemorrhage; Cerebral infarction; Family history; Stroke; Taiwan; |
語 文 | 英文(English) |
英文摘要 | Objective: Family history is a risk factor for stroke. The objective of this study was to investigate whether stroke subtypes and gender might have a familial contribution to stroke. Methods: Detailed family history analysis was used to investigate the parents or siblings of the probands and controls who were classified into 3 groups: probands, outpatient controls, and spouse controls. The lifetime risk (LTR) of stroke was estimated using a Cox proportional hazard model. Results: The 684 probands and controls yielded 1066 parents and 3247 siblings. Compared to the parents and siblings of the controls, those of the stroke patients had a significantly higher LTR. The findings were consistent between probands with cerebral infarction (CI) or cerebral hemorrhage (CH), independent of diabetes, hypertension, and smoking. With regard to gender, family history of stroke was significant for both parents and siblings of the CH or CI patients, but not for the fathers of CI patients and sisters of CH patients. The family history of stroke was associated with an increased risk of stroke of all subtypes, except cardioembolism. Conclusions: This study supported the familial contribution to stroke in the case of both CI and CH but not cardioembolism, independent of the established risk factors for stroke. Gender differences in familial clustering of stroke subtypes were also revealed. These results warrant further molecular genetic studies. |
本系統中英文摘要資訊取自各篇刊載內容。