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題 名 | The Epidemiological Trends and Impact of Resistance on the Outcome of Neonatal Omphalitis: 12 Years Experience in a Medical Center=臍帶炎之致病菌種變化及抗藥性對於臨床嚴重程度的影響 |
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作 者 | 張振宗; 林淑敏; 王曉萍; 陳英堯; 謝凱生; | 書刊名 | Clinical Neonatology |
卷 期 | 13:2 民95.12 |
頁 次 | 頁55-59 |
分類號 | 417.517 |
關鍵詞 | 臍帶炎; 致病菌種; 抗藥性; 新生兒; Omphalitis; Staphylococcus aureus; Escherichia coli; Newborn; Resistance; |
語 文 | 英文(English) |
英文摘要 | Objectives: To understand the epidemiological trends and impact of resistance on the outcome of neonatal omphalitis, we investigated the features of omphalitis cases that occurred in a medical center over the past twelve years. Materials and Methods: The medical records of patients with omphalitis between January 1994 and December 2005 were reviewed retrospectively. A total of 64 patients with inflammatory change of the umbilical stump or the surrounding tissue were enrolled. The patients were divided into two groups in different time periods to compare the epidemiological trends. Results: Staphylococcus aureus and Escherichia coli were the leading pathogens of neonatal omphalitis. Infections of S. aureus increased significantly in the latter 6 years. The proportion of patients with resistant bacteria did not increase (42.4% vs. 46.4%, p=0.754) over time, while the occurrences of those with methicillin resistant staphylococcus aureus (MRSA) did increase (23.5% vs. 43.5%, p=0.191). There was no difference in the systemic signs, laboratory data or hospital stay between the presence and absence of resistant bacteria groups. Conclusions: S. aureus caused the majority of omphalitis infections and the emergence of MRSA is noteworthy. In vitro resistance is not indicative of clinical severity and further studies are necessary to aid decisions on the optimal management of omphalitis. |
本系統中英文摘要資訊取自各篇刊載內容。