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題 名 | 跟骨定量超音波儀應用於健康篩檢之適當性評估=Evaluation of the Application of Quantitative Ultrasound of the Calcaneus in Health Examination |
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作 者 | 羅煥鉅; 王梅芳; 黃立宗; 郭俞良; | 書刊名 | 中華放射線醫學雜誌 |
卷 期 | 30:4 民94.08 |
頁 次 | 頁213-216 |
分類號 | 416.13 |
關鍵詞 | 雙能X光骨密度儀; 骨質疏鬆; 定量超音波儀; 跟骨; Dual X-ray absorptiometry; Osteoporosis; Quantitative ultrasound; Calcaneus; |
語 文 | 中文(Chinese) |
中文摘要 | 本研究嘗試利用統計的方法分析雙能X光骨密度儀與跟骨定量超音波儀診斷結果之差異,並評估跟骨定量超音波儀用於健康篩檢的適當性。 總共有98 位的更年期前後婦女(平均49 ±12 歲)參與這次的研究,利用雙能X光骨密度儀與跟骨定量超音波儀量測病患的骨密度,並將結果以成對T檢定與線性回歸來加以分析,再利用加權卡帕統計法分析其間的一致性。 由成對試驗比較雙能X光骨密度儀與跟骨定量超音波儀的結果得到t值為5.943(P < 0.001),顯示兩者之間有統計上的顯著差異。而利用線性回歸計算出兩者之間的皮爾森相關係數為0.714(P < 0.0001)。經加權卡帕統計法分析發現兩者的診斷結果並不一致,其一致性只達到尚可的程度(kappa score =0.258, P < 0.0001)。 現階段跟骨定量超音波儀不能取代雙能X光骨密度儀,必須先以雙能X光骨密度儀作診斷標準,再將跟骨定量超音波儀依此標準作調整校正,以提昇診斷之精確性與可信賴度,始可運用於健康篩檢。 |
英文摘要 | The aim of our study was to evaluate the difference and agreement between quantitative ultrasound (QUS) and dual X-ray absorptiometry (DXA) using statistical method, which is suitable for the health examination. Ninety-eight consecutive patients (female, 49 ± 12 years old) of perimenopause were examined in this study. DXA of the lumbar spine was performed to acquire the BMD values and were expressed as T-score. At the same session, the calcaneus of the same patients was examined with QUS. Paired T-test and linear regression were performed to observe the relationship between QUS and DXA. The level of agreement was analyzed with weighted kappa (wk) statistics. The paired T-test for comparison of T-score of DXA and QUS showed t-value about 5.943 (P < 0.001), which was statistical significance. Pearson’s correlation coefficient for the comparison of QUS with DXA was R = 0.714 (P < 0.0001). Using single proportion test, the diagnostic percentage of osteoporosis was also significant difference (significant statistic) of between the DXA (11.2%) and QUS (20.4%) (Z = 2.135, 0.028 < P < 0.03). By weighted kappa statistic of T-score, the diagnostic disagreement was found between QUS and DXA, the agreement was fair (kappa score = 0.258, P < 0.0001). QUS cannot replace DXA; it may be an alternative method for high-throughput screening tool for osteoporosis in health examination if it had been standardized as DXA. QUS is not recommended for diagnosis and monitoring of osteoporosis. |
本系統中英文摘要資訊取自各篇刊載內容。