查詢結果分析
相關文獻
- Three Dimensional Cone-beam Reconstruction of Micro Computed Tomography in the Breast Specimen
- 探討乳癌病患於錐狀射束電腦斷層旋轉軸與平移軸擺位誤差轉換之可行性
- The Differences between EPI and 4D-CBCT in Evaluating Inter-fraction Setup Errors for Breast Cancer Radiotherapy
- The Effects of Pesticides Chlordane, Dieldrin and Endosulfan on the Growth of Human Breast Cancer Cell Lines MCF-7 and SK-BR-3
- Prognostic Factors in Node-Negative Breast Cancer Patients: The Experience in Taiwan
- Cystic Hypersecretory Intraductal Carcinoma of the Breast--Case Report
- Timing of Shoulder Exercise after Modified Radical Mastectomy: A Prospective Study
- 前哨淋巴掃描診斷乳癌早期轉移
- Measurement of the Quality of Life during Different Clinical Phases of Breast Cancer
- The Prognostic Significance of Pathologic Characteristics of Breast Cancer Patients in Taiwan
頁籤選單縮合
題 名 | Three Dimensional Cone-beam Reconstruction of Micro Computed Tomography in the Breast Specimen=微型電腦斷層之三維錐狀射束影像重組在乳房檢體之應用 |
---|---|
作 者 | 闕河翔; 陳志成; 蕭穎聰; 謝育仁; | 書刊名 | Journal of Medical and Biological Engineering |
卷 期 | 24:2 2004.06[民93.06] |
頁 次 | 頁115-120 |
分類號 | 416.14 |
關鍵詞 | 錐狀射束; 乳癌; T-FDK演算法; 微型電腦斷層儀; 三維影像重組; Cone-beam; Breast cancer; T-FDK algorithm; MicroCT; 3D reconstruction; |
語 文 | 英文(English) |
中文摘要 | 有關乳房組織切片檢體的檢查,在傳統上只能以顯微鏡的方式來檢查。雖然顯微鏡可以提供很好的空間解析度,但卻只能觀察到一個很薄的切面,因此,如果所欲觀察的微鈣化點不在這個切面的範圍之內,我們便無法觀察到它。為了解決這個問題,我們利用微型電腦斷層儀來對檢體取像,而這個微型電腦斷層儀是使用一個電子衝擊電荷耦合裝置來做為X光的偵檢器。這個研究的目的在於研究三維錐狀射束微型電腦斷層造影術在乳房組織切片檢體的應用及評估。我們以平行射束、扇狀射束和錐狀射束三種不同的影像重組演算法來做檢體的劉象重組,在這個實驗中,我們是以tent Feldkamp-Davis-Kress method (T-FD)來做為錐狀射束影像重組的演算法。我們從立方體假體的影像中以t-test分析影像的變異係數和對比度,發現以T-FDK演算法重組的影像中很明顯的改進。在評估臨床的資料上,我們可以在使用T-FDK演算法的影像中很明顯的觀察到在檢體中的微鈣化點,而在使用一般濾波反投影法的影像中卻無法看到。而且我們可以將影像重構,以三維的方式來表現,並輔以三維的電腦輔助診斷,來幫助臨床上乳癌的診斷及分期。然而,還是有一些因為濾波反投影法造成的假影,我們希望將來可以利用統計式疊代重組法來減少相關的假影。 |
英文摘要 | Traditionally, the specimen obtained from a breast biopsy can only be examined by a microscope. Although the resolution of microscope is high, it can only examine one thin section at a time. Hence, the microcalcifications next to the observed section may be missed. To solve for this problem, we acquire the specimen by a 3D micro computed tomography (microCT) with electron bombarded charged coupled device (EBCCD). The objective of this study was to implement and evaluate the 3D cone-beam reconstruction algorithms for the breast specimen using microCT. We have reconstructed the projections of specimen by parallel-beam, fan-beam, and cone-beam algorithms. For the cone-beam algorithm, we used the tent Feldkamp-Davis-Kress method (T-FDK) in this research. To evaluate the performance, we computed the coefficient of variation (CV) and contrast in the reconstructed images obtained from a cubic phantom, and analyzed the result by a t-test. From the results, we found that significant advantage of T-FDK over others. For the breast specimen, the microcalcifications can be easily identified in the images reconstructed using the T-FDK algorithm, but not in those reconstructed from the filtered backprojection (FBP). We then displayed these reconstructed images in 3D, and applied a 3D computer-aided diagnosis tool for classifying breast cancer. However, there are still some artifacts caused by these analytical reconstruction methods. For the future work, we plan to apply statistical iterative reconstruction methods in the microCT reconstruction, and expect the statistical reconstruction methods can reduce these artifacts. |
本系統中英文摘要資訊取自各篇刊載內容。