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頁籤選單縮合
題名 | 24小時超級馬拉松對跑者肝膽功能之影響=The Effects of 24 Hours Ultramarathon on Liver Function |
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作者 | 黃奕仁; 吳慧君; 陳文茹; 林孟賢; Huang, Yi-jen; Wu, Huey-june; Chen, Wen-ju; Lin, Meng-shyan; |
期刊 | 大專體育學刊 |
出版日期 | 20040200 |
卷期 | 6:1 2004.02[民93.02] |
頁次 | 頁275-283 |
分類號 | 528.9012 |
語文 | chi |
關鍵詞 | 24小時超級馬拉松; 肝膽功能; 膽紅素; 肝臟酵素; 乳酸脫氫酶; 24 hours ultramarathon; Liver function; BIL; GOT; GPT; LDH; |
中文摘要 | 本研究目的在探討24小時超級馬拉松跑後恢復期9天內肝膽功能之變化情形。11名於「2002年東吳國際超級馬拉松暨IAU亞洲24小時錦標賽」完成比賽且成續超過100公里以上之參賽選手,平均年齡45.1±8.77歲、身高166.8±6.23公分、體重60.6±6.96公斤,於賽前一天、賽後即刻、賽後48小時及第9天接受抽血,以觀察肝膽功能之變化情形。結果發現總膽紅素和直接膽紅素於賽後即刻顯著升高(p<.05),48小時後恢復正常;血中總蛋白(TP)、白蛋白(ALB)和球蛋白(GLO)於賽後即刻無變異,但48小時後顯著減少(p<.05),第九天漸漸恢復,惟仍明顯低於賽前值;鹼性磷酸酶(ALP)、血清麩草酸轉胺基酶(sGOT)和血清麩丙酮酸轉胺基酶(sGPT)於賽後即刻分別顯著升高了1.2、14.5、3.4倍(p<.05),48小時後下降,惟sGOT和sGPT仍顯著高於賽前,且超出正常範圍甚多,第9天時除sGPT外,二者均恢復正常值;γ-麩胺基轉移酶(γ-GT)於賽前賽後各階段均無差異;乳酸脫氫酶(LDH)賽後顯著升高3.8倍,48小時後輕微下降,但直至第9天之推測值仍顯著高於賽前。另外,將選手年齡和比賽成績與各項指數做相關研究後發現,年齡與賽後48小時球蛋白成負相關,選手成績與賽後sGOT、sGPT和LDH值有顯著的正相關存在;各項指數之間,sGOT、sGPT和LDH有明顯的正相關,和膽紅素及ALP則無相關存在,賽後48小時的sGPT與球蛋白有明顯正相關。由結果得知以下結論:選手完成連續24小時之比賽後,產生某種程度的溶血及肝臟損傷現象;賽後48小時紅血球破壞率增加之情況已經消除,同時肝臟的損傷仍未恢復;至第9天時,肝膽功能已大致恢復,但血清中蛋白質的補充則尚未完成。選手sGOT、sGPT和LDH於賽前超出一般正常值,可能是訓練或疾病造成的結果;肝膽功能之損傷與年齡無關,但與選手成績成正相關,表示完成工作量越多,肝臟因能量長時間超量的供應,產生較大的損傷,但至賽後第9天可大致恢復。 |
英文摘要 | The purpose of this study was to investigate the effects of a 24 hours ultramarathon race on the runner's liver function. Eleven participants' (average age 45.1± 8.77 yr, height 166.8± 6.23 cm, weight 60.6±6.96 kg)blood samples were obtained before, at the end, after 48 hours, and 9 days after the 2002 International 24h Race IAU Asia 24-Hour Championship for standard blood biochemical test. The results showed that at the end of race, runners' totalbilirubin (BIL-T) and direct-bilirubin (BIL-D) increased significantly (p<.05), alkaline (ALP), GOT, GPT, LDH significantly increased 1.2,14.5, 3.4, 3.8 folds respectively, total protein (TP), ALB, GLO,γ-GT did not change significantly. Forty-eight hours after the race, GOT, GPT, LDH were a little decreased but still 7.3, 3.6, 3.1 times higher than the original level. TP, ALB and GLO were decreased significantly, BIL- T, BIL-D, and ALP recovered to the original level before the race. Nine days after the race, most of the functional indexes recovered to standard levels, but the TP and ALB were still significantly lower than the original level. Working amounts were positively related to liver damage level. According to the results we concluded that after 24 hours ultramarathon race, runners' increasing liver enzyme level revealed the damage of liver cells, but the increasing BIL should be due to the higher removal rate of declined red blood cells and not due to the mean blockage of bile duct. More working amount induced more damage to the liver, but it could recover after approximately 9 days. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。