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題名 | Endoscopic Therapy with Topic Formalin for Treatment of Refractory Lower Gastrointestinal Bleeding=以福馬林經由內視鏡治療頑固性下腸胃道出血 |
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作者 | 糠榮誠; 趙培傑; 吳昌杰; 李家政; 葉建志; 蕭正文; 饒樹文; | 書刊名 | Journal of Medical Sciences |
卷期 | 23:3 2003.06[民92.06] |
頁次 | 頁161-164 |
分類號 | 416.243 |
關鍵詞 | 福馬林; 頑固性下腸胃道出血; Lower gastrointestinal bleeding; Topic formalin; |
語文 | 英文(English) |
英文摘要 | Background: opic formalin was widespread used for treatment of radiation-induced proctitis. Our aim was to assess the safety and efficacy of topic formalin for treatment of refractory lower gastrointestinal bleeding. Methods: Twenty-six patients with intractable lower gastrointestinal bleeding treated with topic formalin were conducted to our study. The sources of bleeding included of diverticulosis in 5, radiation proctitis in 4, ulcerative colitis and proctitis in 2, ischemic colitis in 3, rectal ulcer in 3, inoperable pelvic malignancy in 3, anorectal trauma in 1, status post hemorrhoidectomy in 2, diversion proctitis in 1, and angiodysplasia in 2. All patients had been treated with traditional measures but these had failed. Nineteen patients were treated with formalin instillation via a colonoscope into rectum and colon. Seven had formalin-soaked cotton directly compressed at bleeding site of rectum via a rigid sigmoidoscope or anoscope. Results: At a mean follow-up of 16 months (range 3 to 28 months), a total of 38 sessions of 26 patients were performed. Twenty-three patients (88%) had no recurrent bleeding and the remaining 3 patients developed recurrent massive hemorrhage required further colectomy. Postoperative complications included of anal pain in 5, fecal urgency in 5, anal ulcer in 2, abdominal cramping in 2, and fever in 1. Conclusions: Both of the formalin instillation and formalin-soaked cotton compression in treatment of refractory lower gastrointestinal bleeding are safe and well-tolerated therapy option. The overall successful rate of ceasing bleeding is 88% of patients. |
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