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題 名 | Invasive Streptococcus Pneumoniae Infections of Children in Central Taiwan=中臺灣地區兒童之侵襲性肺炎球菌感染 |
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作 者 | 馬瑞杉; 陳伯彥; 遲景上; 林進福; 劉有增; | 書刊名 | 微免與感染雜誌 |
卷 期 | 33:3 2000.09[民89.09] |
頁 次 | 頁169-175 |
分類號 | 417.5351 |
關鍵詞 | 兒童; 肺炎球菌感染; Invasive pneumococcal infections; Penicillin nonsusceptible streptococcus pneumoniae; |
語 文 | 英文(English) |
英文摘要 | We carried out a retrospective study on childhood invasive pneumococcal infections (IPI) diagnosed from the January 1990 through the April 2000 at a medical center in central Taiwan. Their clinical features, outcome of the patients and the resistance patterns of the isolates were analyzed. A total of 95 clinical isolates from 72 patients younger than 14 years of age were included in this study. Of these 72 patients, 51 had bacteremia, 28 meningitis, 14 bacteremic pneumonia, 12 pleural empyema, eight otitis media, four arthritis, three sinusitis, two periorbital abscesses, one deep neck infection, one psoas muscle abscess, one peritonitis, one urinary tract infection, and one cutaneous infection. Ancillary diagnostic tests, including Gram stain smears and latex agglutination tests, were applied and the sensitivities were 86.2% and 54.3%, respectively. The prevalence rate of penicillin nonsusceptible Streptococcus pneumoniae has increased dramatically since 1995 in central Taiwan, with rates of 5.6% and 74.1% before and after 1995, and the overall mortality rate was 20.8% and 53.3% respectively. Ten of 19 children (52.6%) with pneumococcal meningitis who survived had long-term sequelae. |
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