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題名 | A Survey of Congenital Heart Disease in Patients with Oral Clefts=唇顎裂病童合併先天性心臟病的研究 |
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作者 | 梁啟迪; 黃嵩雀; 賴瑞斌; | 書刊名 | 臺灣兒科醫學會雜誌 |
卷期 | 40:6 民88.11-12 |
頁次 | 頁414-417+465 |
分類號 | 417.64111 |
關鍵詞 | 先天性心臟病; 唇裂; 顎裂; 盛行率; Congenital heart disease; Cleft lip; Cleft palate; Prevalence; |
語文 | 英文(English) |
中文摘要 | 本研究的目的,為回溯性調查唇顎裂病童合併先天性心臟病的盛行率。研究對象 為 1991 年到 1998 年, 曾到本院住院, 年齡小於 15 歲的唇顎裂病童。 我們共收集了 1148 名唇顎裂的病例,經統計有 62 名合併先天性心臟病,盛行率為 5 . 4%。 其中男孩 有 38 名,女孩有 24 名。我們將所有唇顎裂的病例分成三組; 第一組是唇裂,第二組是唇 裂加顎裂,第三組是顎裂。經統計第一組有 10 名,第二組有 27 名,第三組有 25 名。在 先天性心臟病的分析,心房中隔缺損和心室中隔缺損是兩種最常見的缺陷,分別佔所有病例 數的 23% 和 21%。 在這 62 名病例中,我們發現有 35 名 (56%),另外合併有其他器官的 異常。其中以中樞神經系統和骨骼系統的異常最常見。本研究的結果顯示,唇裂這一組的病 童,合併先天性心臟病的病例數,比唇裂合併顎裂或顎裂這兩組來得少; 合併有其他器官的 異常的病例,也在後面這兩組有先天性心臟病的唇顎裂病童中較多。因此,我們的結論是, 針對這兩組有先天性心臟病的唇顎裂病童,臨床醫師有必要做更詳細的檢查,期使更多的器 官異常,在這類病童都能獲得更早期的診斷和治療。 |
英文摘要 | The purpose of this study is to determine the prevalence of congenital heart disease in patients with cleft lip and/or palate. We undertook a retrospective study of 1 148 cases, age < 15 years old, with cleft lip and/or palate from January 7997 to December 1998, of which congenital heart disease was associated in 62 patients. The overall prevalence of congenital heart disease in patients with clefts was 5.4%. Of the 62 patients, there were 38 boys and 24 girls. We classified clefts into one of three cate.gories; group 1: cleft lip alone; group 2: cleft lip and palate: group 3: cleft palate alone. The cleft lip and palate (group 2) was present in the majority (27 of 62: 44%) of patients with congenital heart disease. Twenty-five patients (40%) had cleft palate, and ten patients (16%) had cleft lip. Isolated atrial septal defect and ventricular septal defect are the two common congenital defects, which presented 23% and 21% of patients, respectively. Apart from congenital heart disease and cleft lip or palate. 56% (35 of 62 patients) had additional abnormalities. Central nervous system and skeletal malformations were the most common associated abnormalities. In our study, congenital heart disease was more common in patients of group 2 and group 3 than of group 1. In addition, there was a significantly greater propor- tion of patients associated with other systemic anomalies in groups 2 and 3 than in group 1 (chi-square x �� = 7.535. p=0.023), but no significant difference was noted between group 2 and group 3. We recommend that it would be appropriate for all cleft patients to receive a routine examination for associated anoma- lies by a pediatrician. With the widespread use of echocardiography and/or brain sonography, the early diagnosis and treatment of these anomalies are possible. |
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