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題 名 | Hyperlipidemia of Normal Pregnancy in Karachi-Pakistan=巴基斯坦正常孕婦中的高血脂症 |
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作 者 | 席曉蓉; 鄭海安; 黃瑒濱; 吳向東; | 書刊名 | The Kaohsiung Journal of Medical Sciences |
卷 期 | 15:9 1999.09[民88.09] |
頁 次 | 頁529-535 |
分類號 | 417.3 |
關鍵詞 | 巴基斯坦; 正常孕婦; 高血脂症; Lipoproteins; Plasma lipids; Pregnancy; |
語 文 | 英文(English) |
中文摘要 | 有報導孕期中血總膽固醇、甘油三酯、低密度脂蛋白膽固醇和高密度脂蛋白膽固醇水平有所升高。然而,許多研究中血脂、脂蛋白與孕期的關係並不一致,而且變化程度也不相同。因此,本實驗完整地研究血脂、脂蛋白在孕期和產褥期的變化,同時也觀察了血脂和其它與懷孕相關因素的關係。檢測了56位孕婦的整個孕期和產褥期及56位非孕婦血漿中膽固醇、甘油三酯及脂蛋白濃度。與對照組相比,血漿中膽固醇、甘油三酯與脂蛋白濃度在妊娠中期有明顯升高,並在妊娠晚期達到最高值。產後24小時內,膽固醇,甘油三酯和所有脂蛋白濃度有顯著降低,但大多數調查對象的膽固醇和甘油三酯在產後4週內乃保持較高的 水平。血清膽固醇的增加似乎與血清甘油三酯有部分關係,但似乎與年齡、體重的增加、懷孕次數及胎兒的性別無關。本研究表明懷孕期間,血脂濃度普遍增高。 |
英文摘要 | During pregnancy, changes in the levels of total cholesterol, triglyceride, low density lipoprotein-cholestrol, and high density lipoprotein-cholestrol have been described, but in the existing literature these effects remain controversial because of inconsistencies. Moreover, the degree of change varies from study to study. Therefore, the present study completely investigated changes in lipids and lipoproteins throughout the pregnancy and in the puerperium. We also investigated whether or not any relation between plasma lipids and other pregnancy related factors exist. Concentrations of cholesterol and triglyceride of total plasma, and lipoproteins were determined in 56 pregnant women throughout the pregnancy and in the puerperium along with 56 non-pregnant women. Compared to control group, concentrations of cholesterol and triglyceride of total plasma and lipoproteins increased significantly during second trimester and reached maximum in the third trimester. Both cholesterol and triglyceride concentrations decreased significantly within 24 hours of delivery and this was reflected in all lipoproteins. In the majority of subjects, cholesterol and triglycerides remained significantly high until 4 weeks of postpartum. The magnitude of the serum cholesterol increment appeared in part to be related to that of serum triglyceride, but these increments appeared to be independent of age, weight gain, numbers of previous pregnancies and sex of the fetus. This study concludes that hyperlipidemia is a common finding during pregnancy. |
本系統中英文摘要資訊取自各篇刊載內容。