頁籤選單縮合
題 名 | Entering the Gene Therapy Era=迎接基因治療的時代 |
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作 者 | 連永豪; 賴麗文; | 書刊名 | 臺灣醫學會雜誌 |
卷 期 | 98:11 1999.11[民88.11] |
頁 次 | 頁718-721 |
分類號 | 418.99 |
關鍵詞 | 基因治療; Gene therapy; Gene transfer; Inherited diseases; |
語 文 | 英文(English) |
英文摘要 | Gene therapy is a new modality with the potential for treating a variety of diseases, inherited or acquired. Although the initial clinical trials, particularly those for cystic fibrosis, have not been successful, the preliminary results of more recent studies of gene therapy for myocardial infarction are encouraging. New plasmids, viral and nonviral vectors, and applications are being developed at a rapid pace. A switch is now inserted in the plasmids so that the therapeutic gene can be turned on and off as needed. A chimeric RNA/DNA oligonucleotide has also been designed so that mutated genes can be converted to normal sequences. These and other novel approaches soon will propel the gene therapy industry into reality. Healthcare providers and educators need to be prepared for the coming of the gene therapy era. |
本系統中英文摘要資訊取自各篇刊載內容。