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題 名 | Pyoderma Gangrenosum in Childhood--Report of a Case and Review of the Literature=小兒壞疽性膿皮症--一病例報告及文獻回顧 |
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作 者 | 賴昌和; 施一新; 曾興隆; | 書刊名 | 中華皮膚科醫學雜誌 |
卷 期 | 17:2 1999.06[民88.06] |
頁 次 | 頁124-131 |
分類號 | 415.725 |
關鍵詞 | 小兒; 壞疽性膿皮症; Pyoderma gangrenosum; Children; |
語 文 | 英文(English) |
中文摘要 | 壞疽性膿皮症為一少見之皮膚潰瘍疾病,而此病罕見於兒童。我們在此報告一個 小兒病例。此病例為三歲八個月大之男孩。病灶為右腳脛前之潰瘍。系列檢查沒有發現任何 全身性之疾病。投與類固醇治療後,潰瘍癒合且追蹤二十個月沒有復發。回顧文獻,我們另 外找到61個小於16歲的病例,分析其臨床變化、合併症、以及治療方法。其中有10例為 嬰兒,其病灶好發於肛門及生殖器周圍。而孩童病例則類似於成人,病灶之分布最常見於下 肢;但頭部、臉部、臀部潰瘍則孩童多於成人。有66%的病患合併有全身性的疾病,其中 以潰瘍性大腸炎最常見。最常用而有效的治療藥物是類固醇。 |
英文摘要 | Pyoderma gangrenosum (PG) is an uncommon ulcerative skin disorder that occurs in all age groups. It rarely occurs in children. We report a case of a 3-year-8-month-old boy with PG on his right leg. No underlying disease was found. He was treated with intravenous steroid and no relapse occurred during 20-month follow-up. We reviewed the childhood cases(≦16 years of age) reported in the literature for the clinical features, associated disorders, and therapy. There were 62 patients in total, including our case. Ten were less than 1 year of age, Infants often had ulcers in the perianal and genital areas. In children, the clinical features were similar to those of adults. The distribution of the lesions in children was similar, often involving the lower extremities. However, ulcers of the head, face, and buttocks were more common in children than in adults. Associating with systemic disease was present in 66% of the cases, ulcerative colitis being most common. The most frequently prescribed treatment for children was systemic corticosteroids, which generally were very effective. |
本系統中英文摘要資訊取自各篇刊載內容。