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題名 | 拋棄式隱型眼鏡對於犬隻角膜傷口癒合的影響=Influence of Therapeutic Soft Contact Lens on Canine Corneal Healing |
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作 者 | 茅繼良; 王敏勝; 林荀龍; | 書刊名 | 臺灣畜牧獸醫學會會報 |
卷期 | 68:1/2 民87.06 |
頁次 | 頁27-35 |
分類號 | 437.66 |
關鍵詞 | 治療型隱形眼鏡; 拋棄式隱形眼鏡; 角膜傷口; 犬; Therapeutic contact lens; Disposable contact lens; Comeal wound; Dog; |
語文 | 中文(Chinese) |
中文摘要 | 治療型隱形眼鏡在臨床角膜疾病的治療效果已被廣泛討論,並且獲得肯定。近年 來,眼科醫師並嘗試以拋棄式隱形眼鏡來取代傳統治療片。而為了探討拋棄式隱形眼鏡對於 角膜傷口癒合的影響,本實驗在 14 隻實驗狗的角膜中央製造了一直徑 8mm, 深約達角膜基 質 1/3 的標準傷口,每隻實驗動物以隨機的方式選取一眼配戴拋棄式隱形眼鏡, 另一眼則 留作對照用,評估兩眼角膜傷口的癒合速率。結果以拋棄式隱形眼鏡處理的眼睛在前 48 小 時的癒合速率明顯慢於對照組 (treated,0.38mm �� /hr vs. control,0.77m �� m/hr), 而在 48 小時之後,實驗組癒合速率增快,對照組反而減慢 (treated,0.84mm �� /hr vs. control,0.59mm �� /hr),兩組的平均癒合時間同樣都是 115.2 小時。實驗結果顯示拋棄 式隱形眼鏡對於角膜傷口末期的癒合過程是有幫助的。但無論如何,拋棄式隱形眼鏡應用於 小動物臨床之前,角膜的癒合情形應該需要更進一步之研究。 |
英文摘要 | Using therapeutic soft contact lens in treating comeal disease has already been widely described. However, the latest developed disposable contact lens has the advantage in patient tolerance and it was not necessary to clean the lenses. In order to evaluate the effect of disposable contact lenses on cornea stromal wound healing in dogs, a central comeal wound (8 mm in diameter, 0.3 mm in depth) was created on both eyes of 14 mongrel dogs. One eye in each dog was chosen randomly for placement of disposable contact lens, and the other eye worked as control. After the calculation with simple linear regression, it was observed that in the first 48 hrs after the comeal defect was made, the disposable contact lens showed delay in the healing, when compared to the opposite eye (0.38 mm �� /hr vs. control 0.77 mm �� /hr). Conversely, during the following stage the healing rate with disposable contact lens was significantly accelerated than the control (0.84 mm �� /hr vs. control 0.59 mm �� /hr).The results of this preliminary study suggest that the disposable contact lens may be beneficial to the comeal healing in the later stage. However, for the ultimate use of such material in small animal practice, the quality and clarity of the healed cornea should be further studied. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。