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題名 | 早期聲門癌以內視鏡二氧化碳雷射顯微手術治療的長期追蹤結果=Endoscopic CO[feaf]Laser Microsurgery for Treating Early Glottic Cancer: Long-Term Follow-Up |
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作者 | 王怡芬; 徐念宗; 張學逸; Wang, Yi-fen; Hsu, Nien-tzong; Chang, Shyue-yih; |
期刊 | 中華民國耳鼻喉科醫學會雜誌 |
出版日期 | 19981000 |
卷期 | 33:5 1998.10[民87.10] |
頁次 | 頁72-79 |
分類號 | 416.8932 |
語文 | chi |
關鍵詞 | 二氧化碳雷射; 內視鏡聲帶切除術; 早期聲門癌; Carbon dioxide laser; Endoscopic cordectomy; Early glottic carcinoma; |
中文摘要 | 背景:使用內視鏡二氧化碳雷射顯微手術來治療早期聲門癌,已被廣為接 受是一簡單、可保存發聲機能且治癒率很高的手術。本文將我們近年來以內視鏡二氧化碳雷 射顯微手術治療早期聲門癌後長期追蹤的結果作一檢討和分析。 方法:自 1986 年 3 月至 1992 年 9 月期間, 我們針對 20 例早期聲門癌患者:包括原位癌 2 例, Tla 聲門癌 15 例,T2 聲門癌 3 例,施行內視鏡二氧化碳雷射顯微手術並術後追蹤至少 62 個月, 以統計 其復發的情形。 結果: 在 20 例中有 2 例病理報告顯示切除邊緣有腫瘤細胞,於術後加作 放射線治療且追蹤期間沒有腫瘤復發; 另有 1 例於術後 60 個月腫瘤復發,但施行全喉切 除術後得以控制病情;統計顯示 5 年的疾病控制率為 95%,而 5 年存活率則為 100%。 結 論: 我們認為內視鏡二氧化碳雷射顯微手是治療日期聲門癌一個相當理想的選擇。 |
英文摘要 | Background: In the treatment of early glottic cancer, there are many treatment options at present. Endoscopic CO �� laser microsurgery had proven to be a good treatment altenative for early glottic cancer in terms of oncological as well as functional results in a simple way. Method: Twenty patients with early glottic cancer in the period from 1986 through 1992 had been treated by endoscopic Co �� laser microsurgery and followed for a minimum of 62 months. Results: Two patients underwent postlaser surgery radiotherapy because the presence of cancer cells at the margins of the excised specimen by histoparthologic examination. A local recurrence of disease developed 60 months later postoperatively in one of these patients but was successfully treated by total laryngectomy, unfortunately this patient died of small cell carcinoma of the lung 32 months later. The 5-year disease control rate was 95% (19 of 20 patients) and the 5-year survival rate was 100% (20 of 20 patients). Conclusions: We concluded that endoscopic CO �� laser microsurgery could be a successful treatment option if careful patient selection and accurate serial histopathologic evaluation are followed. |
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