頁籤選單縮合
| 題 名 | Risk Factors of Non-Arteritic Anterior Ischemic Optic Neuropa Thy (NAION): Ocular or Systemic=非動脈炎性前缺血性視神經病變的危險因子探討:全身性或眼球性因子的比較 |
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| 作 者 | 蔡榮坤; 劉怡增; 蘇明揚; | 書刊名 | The Kaohsiung Journal of Medical Sciences |
| 卷 期 | 14:4 1998.04[民87.04] |
| 頁 次 | 頁221-225 |
| 分類號 | 416.73 |
| 關鍵詞 | 前缺血性視神經病變; Non-arteritic anterior ischemic optic neuropathy; Risk factors; Refraction; |
| 語 文 | 英文(English) |
| 中文摘要 | 我們回溯1994年到1996年在高雄中和紀念醫院診斷為前缺血性視神經病變的22例病人,並探討發生的危險因子。危險因子分為眼球性及系統性兩種;眼球性因子包括屈光情況、眼壓及對側眼視神經盤凹陷的比例。系統性因子則包括糖尿病、高血壓及心血管疾病。分析的結果包括:(l) 僅有22.6%的病人有系統性的危險因子。(2) 眼壓對前缺血性視神經病變的發生不具特異性。(3) 72.6 %病人對側眼視神經盤凹陷的比例不超過0.1。(4) 不論患側眼或對側眼,有90.9%的病人屈光情況為遠視或正視眼,僅有9%的病人為近視眼。眼球性對於全身性因子的比較在統計學上有明顯的意義。本研究中,前缺血性視神經病變的發生與系統性的危險因子的相關性不若先前的研究那麼高。相反的,因為狹小視神經盤凹陷的擁擠效應而造成視神經盤血流障礙的惡性循環,可能在前缺血性視神經病變的發生上扮演極重要的角色。此外,遠視或正視眼較近視眼容易發生前缺血性視神經病變。可能是因為這一類病人視神經盤缺乏顯側凹陷,使得狹小視神經盤凹陷的血流障礙更增加不利的因子。本研究中,眼球性的危險因子似乎較系統性因子對於前缺血性視神經病變的發生具有更強烈的相關性。 |
| 英文摘要 | We retrospectively analyzed 22 patients with non-arteritic anterior ischemic optic neuropathy (NAION) seen at Chung-Ho memorial hospital between 1994 and 1996 to investigate the risk factors of NAION. The risk factors were divided into two groups: ocular and systemic. The ocular factors include refractive state, intraocular pressure, and cup-disk ratio of fellow eye. The systemic factors include diabetes, hypertension and cardiovascular diseases. The analysis revealed:(1)only 22.6% of patients with NAION have systemic risk factors;(2)intraocular pressure is not specific to NAION;(3)most of fellow eyes(72.6%)have cup-disk ratio not more than 0.1; and (4) most patients (90.9%) are hyperopic or emmetropic, only 9% of patients are myopic in either affected or fellow eyes. The statistical comparison between ocular (including cup-disk ratio and refractive state) and systemic factors is significant. The correlation with systemic factors in our study was not so high as previous study had reported. On the contrary, crowding effect of small cup-disk ratio, which induces a vicious circle of generally circulatory compromised disk, may play an important role in NAION. Besides, hyperopic or at least emmetropic eyes are more prone to NAION than myopic eyes. This may be due to lack of flattening of the temporal excavation, therefore adding a predisposing factor to a generally circulatory compromised disk. The risk factors associated with NAION seem more strongly correlated with ocular factors than with systemic factors. |
本系統中英文摘要資訊取自各篇刊載內容。