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題 名 | Acinetobacter Calcoaceticus-Baumannii Complex Bacteremia:Analysis of 82 Cases=Acinetobacter calcoaceticus-baumannii Complex菌血症:82病例之分析 |
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作 者 | 林聖一; 王永衛; 馮長風; 劉尊榮; 劉正義; | 書刊名 | 微免與感染雜誌 |
卷 期 | 31:2 1998.06[民87.06] |
頁 次 | 頁119-124 |
分類號 | 419.38 |
關鍵詞 | Acinetobacter calcoaceticus-baumannii complex菌血症; 院內感染; Acinetobacter calcoaceticus-baumannii complex; Bacteremia; |
語 文 | 英文(English) |
中文摘要 | 過去兩年多來,共收集82例院內感染Acinetobacter calcoaceticus-baumannii complex 菌血症,其中有 28 例是併有多種細菌感染,大多數病患是罹患重症。 26 例是癌 症病患,40例曾經或正住在加護病房,17例接受手術。容易造成A. calcoaceticus-baumannii complex 菌血症原因有中心靜脈導管置留、氣管插入或氣切形成 術、先前抗生素的使用與長期住院。amikacin,tobramycin 及 ceftazidime 是抗生素敏感 性試驗中較有效的抗生素。 82 例中有 32 例 (39 % ) 死亡,其中 19 例 (23 % ) 直接 肇因於敗血症,影響死亡率因素包括多種病菌感染、抗生素選擇不當、與先前抗生素使用。 其中較有趣是使用不當抗生素者大都死亡。 因此對於治療 A. calcoaceticus-baumannii complex 菌血症,重要的是早期診斷與適當抗生素的治療。 |
英文摘要 | Eighty-two cases of Acinetobacter calcoaceticus-baumannii complex bacteremia were identified during a 33-month period, from November 1993 to July 1996, at the Veterans General Hospital, Taipei. All cases were due to hospital-acquired infections, with 28 cases of polymicrobial bacteremia. Most patients had severe debilitating conditions:26 had malignancies, 40 required stay in Intensive Care Unit and 17 had undergone major operations. The main predisposing factors included central venous catheterization, endotracheal intubation or tracheostomy, prior antibiotic therapy and prolonged hospitalization. Amikacin, tobramycin, and ceftazidime were the most effective agents in vitro against A. calcoaceticus-baumannii complex. 32 patients (39%) died during hospitalization, 19 of the cases (23%) directly attributed to septicemia. Factors that adversely influenced mortality included polymicrobial bacteremia, inappropriate antimicrobial therapy and prior antibiotic treatment. Of particular interest is the fact that none of the patients who did not receive appropriate antimicrobial therapy survived. Early diagnosis and appropriate antibiotic therapy are critical for improving the prognosis of A. calcoaceticus-baumannii complex bacteremia. |
本系統中英文摘要資訊取自各篇刊載內容。