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題名 | 過敏性鼻炎患者之中醫體質研究=The Study of the Physical Constitution among Allergic Rhinitis Patients in Chinese Medical Perspective |
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作者 | 蘇奕彰; |
期刊 | 行政院衛生署中醫藥年報 |
出版日期 | 19980500 |
卷期 | 16:1 1998.05[民87.05] |
頁次 | 頁99-147 |
分類號 | 413.52 |
語文 | chi |
關鍵詞 | 過敏性鼻炎; 中醫; 體質; 臨床試驗; 辨證模式; Allergic rhinitis; Chinese medicine; Physical; Constitution; Clinical trials; |
中文摘要 | 這是一個臨床試驗研究,主要目的在研究過敏性鼻炎患者之中 醫體質特性及中醫體質辨證模式治療本病之療效。研究中採隨機分 組及雙盲試驗,選用桂枝湯及知柏地黃湯治療53位過敏性鼻炎患 者,並觀察其臨床症狀、體徵與實驗室指標,以及中醫體質診斷類 型。結果以卡方檢定、Anova、多變量分析中之多元尺度法及符號檢 定進行分析。 研究之結果顯示:過敏性鼻炎患者之體質類型頻率以陰虛質、 氣虛質和痰濕質較;高以多元尺度法更可將患者症狀分成陽氣虛及 陰血虛兩大群。在接受兩種中藥治療後,除痰濕質外,患者體質類 型頻率均下降,且患者臨床症狀、體徵與疾病活動度積分均獲得顯 著改善。研究中還顯示,桂枝湯對陽氣虛及陰血虛患者均有顯著療 效;而知柏地黃湯則僅對陰血虛患者有顯著療效。 這些研究結果,不僅有助於了解過敏性鼻炎患者之體質特性, 及中醫體質療法之療效,同時針對辨證治療模式之探討,對中醫跨 越經驗醫學進入科學研究上,也是一項重要的嘗試。 |
英文摘要 | This is a study of clinical trial. We focus on the constitutional characteristics of Chinese Medicine, and the effects among allergic rhinitis patients by using syndrome differentiation and treatment in Chinese medical perspective. The random grouping and double-blind case-control methods were used. The Decoction of Cinnamon Twigs and Decoction of Rhizome, Phellodendri and Rehmannia were taken by 53 allergic rhinitis patients for 2 months, then their clinical symptoms, signs, laboratory data, and Chinese medical constitutional types had been recorded. The data was analyzed with Chi-square test, Anova test, multidimentional scaling and Sign test. The result indicates that: on the distribution tendency of constitutional types for allergic rhinitis patients is predominant by Yin-Deficiency type, Phlegm-Wetness type and Chi-Deficiency type. Using multidimentional Scaling on clustering the constitutional symptoms, two obvious groups are also found, one is Yan-Chi-Deficiency type, the other is Yin-Blood-Deficiency type. After the treatment of both drugs, the distribution tendency of constitutional types is decreased except Phlegm-Wetness type, and the clinical symptoms, signs, and scale for disease activity index also are much improved. Besides, the Decoction of Cinnamon Twigs shows effects in both Yan-Chi-Deficiency type and Yin-Blood-Deficiency type of patients, but Decoction of Rhizome, Phellodendri and Rehmannia only in Yin-Blood-Deficiency type. These study results not only can help us understanding the constitutional characteristics and treatment effects on allergic rhinitis patients, but also serve as a stepping stone for Chinese Medicine crossing over the traditional medicine experiences and getting into the modern scientific researches by studying the methodological model of using syndrome differentiation and treatment in Chinese medical perspective. |
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