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題名 | Helicobacter Pylori Infection in Patients with Chronic Renal Failure=慢性腎衰竭病人之幽門曲狀桿菌感染 |
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作者姓名(中文) | 李永康; 高嘉鴻; | 書刊名 | 中國醫藥雜誌 |
卷期 | 2:4 1997.12[民86.12] |
頁次 | 頁208-213 |
分類號 | 415.815 |
關鍵詞 | 幽門曲狀桿菌; 慢性腎衰竭; Helicobacter pylori; Chronic renal failure; |
語文 | 英文(English) |
中文摘要 | 噁心、嘔吐、腹脹及消化不良是慢性腎衰竭病患常見的士訴。而這些症狀被認為與幽門曲狀桿菌的感染有關。本研究的目的茌評估幽閉桿菌於慢怕腎衰竭病患的發生率並比較腹部症狀存茌及實驗室數據與幽門桿菌感染的相關性。共有38位慢性腎衰竭病患進入本研究中,其中21位接受常規血液透析至少四個月,其中I5位有上消化道的症狀。碳-l4尿素吸氣試驗被用來診斷幽門桿菌感染。結果顯示38位病患中有20位(52.6%)百感染,21位接受血液透析病人中百10位(47.6%)百感染,而17位末接受血液透析病人中有10位(58.8%)有感染。此外15位有上消化道症狀病人中有8位(53.3﹪)有感染,23位沒有症狀病人中百12位(52.2%)有感染。接受血液透析及百症狀的8位病人中,3位(37.5%)有感染,接受血液透析而妞症狀的13位病人中,7位(53.8%)百感染:末接受血液透析但百症狀的7位病人中,5位(71.4%)有感染,未接受血液透析且無症狀的10位病人中5位(50.0%)有感染。統計分析結果顯示:不論病人是否接受血液透析或有無症狀,皆與幽門桿菌的感染有關。而且吸氣試驗的結果與所有實驗室數據皆無相關性。吾人結果顯示慢性腎衰竭病人有無接受血液透析與幽門桿菌感染之機率高低無相關性,而且幽門桿菌感染之機率高低與有無上消化道的症狀及所百實驗室數據皆無相關性。 |
英文摘要 | Nausea, vomiting, abdominal fullness and dyspepsia are common complaints of patients with chronic renal failure (CRF). These symptoms are thought to be likely related to Helicobacter Pylon (HP) infection. The aim of this study is to evaluate (1) whether receiving regular haernodialysis (HD) will change the prevalence of HP infection and (2) the relationship of HP status and the presence of abdominal symptoms and some laboratory parameters in patients with CRF receiving and not receiving HD. Thirty-eight patients with CRF were enrolled in this study. Twenty-one of the 38 patients had been receiving regular HD for at least four months prior to the study. Fifteen of the 38 patients had upper gastrointestinal symptoms/signs (Gl Sx). The carbon-14 urea breath test (C14-UBT) was used to diagnose HP infection. Among the 38 patients, 53% (20/38) had a positive C14-UBT for HP infection. The incidences of HP infection were 48% (10/21) in dialyzed patients and 59% (10/17) in undialyzed patients, respectively. In addition, among all subjects, the incidences of HP infection were 53% (8/15) in patients with upper Gl Sx and 52% (12/23) in patients without; upper Gl Sx, of which the incidences were 38% (3/8) and 54% (7/13) in dialyzed patients, and were 71% (5/7) and 50% (5/10) in undialyzed patients respectively. The differences in the incidences of HP infection among dialyzed and undialyzed patients, as well as patients with and without upper Gl Sx, were not statistically significant. The results of the C14-UBT were not correlated with any of the following parameters analyzed in this study: serum level of BUN, creatinine, creatinine clearance rate (CCr), and duration of HD in CRF patients. Our results suggest that HD might not influence HP infection in CRF patients. In addition, HP prevalence is not related to the presence of Gl Sx or other parameters. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。