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頁籤選單縮合
題名 | Analysis of Total IgE and Allergen-Specific IgE Antibody Levels of Allergic Children in Taiwan=臺灣地區過敏病童IgE及過敏原專一IgE之探討 |
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作者姓名(中文) | 羅少甫; 江伯倫; 謝貴雄; | 書刊名 | 中華民國小兒科醫學會雜誌 |
卷期 | 38:5 民86.09-10 |
頁次 | 頁375-385+405 |
分類號 | 417.596 |
關鍵詞 | 支氣管性氣喘; 過敏性鼻炎; 異位性皮膚炎; 塵蟍; 過敏原專一免疫E球蛋白; Bronchial asthma; Allergic rhinitis; Atopic dermatitis; House dust mite; Allergenspecific IgE; |
語文 | 英文(English) |
英文摘要 | 隨時代技術進步,分析過敏原的方式也漸趨多樣。本研究用 Pharmacia-CAP 系統 檢測造成過敏性疾病如支氣管氣喘,過敏性鼻炎,異位性皮膚炎及蕁麻疹的過敏原。392 位 小朋友於 84 年 3 月至 84 年 8 月到臺大醫院小兒部就診,被囊括入本研究中。結果如下 :(1) 392 位小朋友包括 82 位支氣管氣喘,70 位過敏性鼻炎,22 位異位性皮膚炎,156 位支氣管氣喘加過敏鼻炎,8 位支氣管氣喘加異位性皮膚炎,12 位過敏性鼻炎加異位性皮 膚炎,42 位三合一疾病(支氣管氣喘加過敏性鼻炎加異位性皮膚炎同時存在)。(2) 塵�� 是臺灣最要的過敏原 (3) 三合一疾病(支氣管氣喘加過敏性鼻炎加異位性皮膚炎同時存在 )的 total IgE 最高,而單一過敏性疾病過敏性鼻炎的 total IgE 最低; 塵�藈M一 IgE 抗體中三合一疾病(支氣管氣喘加過敏性鼻炎加異位性皮膚炎同時存)的塵�藈M一 IgE 抗 體最高,而單一疾病過敏性鼻炎的塵�藈M一 IgE 體抗最低。(4) 異位性皮膚炎 / 蕁麻疹的 過敏病人中蛋白及牛奶過敏及異位性皮膚炎最重要的禍首,而食物過敏原僅只於皮膚過敏中 較有意義。此外,過敏性疾病愈複雜嚴重 IgE 愈高。 c disease in the Taiwan area. (3) Total IgE level is the highest in three combined allergic disease (BA+AR+AD)[2179.9 ± 504.2 KU/L] and lowest in single disease (AR)[503.1 ± 84.8 KU/L]. Mite-specific IgE (D. p+D. f-specific IgE) concentration is also the highest in three combined disease (BA+AR+AD)[499.1 ± 86.0 KU/L] and lowest in AR [159.5 ± 47.5 KU/L], (4) elevated specific IgE antibody to egg white and milk were found in 68.4% and 47.4% of patients with AD and/or urticaria. In conclusion, these data suggest that house dust mites, are the most important allergens in respiratory allergy as well as in atopic dermatitis, while food allergens play relatively important roles only in skin allergy. Furthermore, the highest IgE level was noted in children with combined allergic diseases. |
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