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| 題 名 | The Study of Pollen and Der p Mite-Specific IgE Antibodies in Children with Allergic Rhinitis=過敏性鼻炎病童花粉及塵蟍特異性IgE抗體之研究 |
|---|---|
| 作 者 | 王允中; 陳五常; | 書刊名 | 中華民國小兒科醫學會雜誌 |
| 卷 期 | 36:1 民84.01-02 |
| 頁 次 | 頁41-49+70 |
| 分類號 | 416.853 |
| 關鍵詞 | 過敏性鼻炎; 特異性IgE抗體; 花粉; 塵蟍; Allergic rhinitis; Specific IgE; Pollen; House dust mite; |
| 語 文 | 英文(English) |
| 中文摘要 | 為了探花粉及塵蟥在臺北地區常年性慢性鼻炎所扮演的角色,我們總共收集54名慢性鼻炎病童的血清,使用購自Pharmacia公司的EIA Kits,測定其血中9種過敏原的特异性IgE抗體,包括塵蟥及8種常見花粉(狗牙根、早熟禾、豬草、車前草、羊蹄、柳、松、相思樹。另外,根據皮膚試驗,吸入性過敏原特异性過敏抗體節檢(Phadiatop),理学检查,过去史及家族史,将所有病童分为过敏性及菲过敏性鼻炎两群。研究结果显示:(1)41名病童被诊断为过敏性鼻炎,占76%;(2)41名(100%)过敏病童及7名(54%)非过敏病童呈陽性塵蟥特异性抗體反應(p<0.005);(3)13名(32%)過敏病童及4名(31%)非過敏病童對一種或一種以上花粉呈陽性反應,而其反應都在2+以下。我們的結論是台北地區的慢性鼻炎病童中約四分之三屬於過敏性,而塵蟥為過敏性鼻炎病童最主要過敏原。至於花粉在台北地區的過敏性鼻炎病童所扮演的角色較不重要。 |
| 英文摘要 | The role of pollens and house dust mites in perennial chronic rhinitis has been investigated for the Taipei area. Fifty-four serum specimens were collected from children with chronic rhinitis. EJA kits (Phadezyme RAST) were used to detect specific IgE antibody of nine allergens, including house dust mite (Der p) and eight common pollens. The children were divided into allergic (AR) and nonallergic (NAR) groups, based on the results of skin tests, inhalant allergen-specific IgE screen (Phadiatop), physical examination, past history and family history. The results showed: (1) 41 (76%) patients were defined as allergic rhinitis; (2) Der p specific IgE was detected in 41 (100%) AR patients and 7 (54%) NAR patients (P<0.005), a strong positive reaction (> 2+) in 83% AR and none NAR patients (P<0.005); (3) one, or more than one, pollen-specific IgE were found in 13 (32%) AR and 4 (31%) NAR patients. No strong positive reaction was detected in either group. The conclusion: (1) three-fourths of the children with chronic rhinitis are allergic by nature; (2) house dust mite is the major allergen of allergic rhinitis; (3) in the Taipei area, pollen does not play an important role for children with allergic rhinitis. |
本系統中英文摘要資訊取自各篇刊載內容。