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題 名 | 犀角與水牛角在兒科領域中的解熱療效評估=Antipyretic Effect of Xi Jiao and Shuiniujiao in Children |
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作 者 | 蔡輔仁; 蔡長海; 彭慶添; 鍾宛君; 郭盛助; | 書刊名 | 中國醫藥雜誌 |
卷 期 | 2:2 1997.06[民86.06] |
頁 次 | 頁114-118 |
分類號 | 414.35 |
關鍵詞 | 犀角; 水牛角; 解熱劑; Xi jiao; Shuiniujiao; Antipyretic effect; |
語 文 | 中文(Chinese) |
中文摘要 | 台灣民間常以犀牛角做為小兒退熱的藥方,由於犀牛瀕臨絕種,本研究期望以科學的角度評估犀牛角的解熱療效,並衡量以水牛角取代犀牛角的可能性。本研究採用雙盲試驗, 選擇年齡在一個月以上,體溫在38℃以上的兒科病人l42人為材料,並排除細菌感染,使用抗生素及類固醇的病人。總共收集142人分為四組,分別給予犀牛角、水牛角、安慰劑及acetaminophen評估其在口服後15分鐘、30 分鐘及45分鐘後的體溫於服藥前的溫差。結果顯示 acetaminophcn 在服藥後15分鐘、30分鐘及45分鐘後都有明顯的降溫作用,犀牛角則僅在15分鐘出現有意義的降溫,水牛角與安慰劑則全部無效。因此,我們建議無論以療效或保育觀點皆不宜以單方犀牛角做為兒科病人的解熱劑。 |
英文摘要 | Rhinoceros horn, also known as Xi jiao (犀角) is often used as an antipyretic drug in Taiwan but it's effects are still unknown. A double-blind study compared the efficacy; safety and the cost of xi jiao, water buffalo horn, also known as shuiniujiao (水牛角 ), a placebo, and acetaminophen in 142 children (three months to nine to nine and a half years) with fever (38.5-40.5 ℃ ). Ear temperatures were obtained before and 15', 30' and 45 minutes after the dose was administered. An obvious antipyretic efficacy was observed in the acetaminophen treated group at 15' � 30', 45' minutes after treatment. Fever reduction was demonstrated in the xi jiao treated group 15 minutes after treatment, but the antipyretic effect was not clear 30 and 45 minutes after treatment. All treatments were well tolerated. No significant clinical or laboratory abnormalities were noted. Since the rhinoceros is becoming extinct and the antipyretic efficacy of xi jiao is less than acetaminophen, xi jiao is not recommended for isolated used in febrile children. |
本系統中英文摘要資訊取自各篇刊載內容。